HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: TFR1 (P02786)
Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)]
Gene: TFRC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30442766, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0044877 - protein-containing complex binding GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 760
+	Hs
		349784 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364224 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364286 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		349051 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364234 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364225 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		TFR1_HUMAN (1-760): 0: 971: 100.00
+	Hs
		364226 RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35		TFR1_HUMAN (1-760): 0: 971: 100.00