HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: RTN1 (Q16799)
Reticulon-1 (Neuroendocrine-specific protein)
Gene: RTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 776
+	Hs
		897894 RAP1B_HUMAN (1-165): 1.02e-61: 191: 56.89		RTN1_HUMAN (1-776): 0: 671: 100.00
+	Hs
		307040 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		RTN3_HUMAN (152-775): 1.93e-117: 380: 26.09
+	Hs
		307017 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		RTN3_HUMAN (152-775): 1.93e-117: 380: 26.09
+	Hs
		918953 RAB1A_HUMAN (4-187): 1.35e-76: 229: 33.33		RTN4_HUMAN (141-776): 1.48e-105: 352: 30.02
+	Hs
		1328148 RAB1B_HUMAN (4-187): 1.35e-75: 226: 33.51		RTN4_HUMAN (141-776): 1.48e-105: 352: 30.02
+	Hs
		914380 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		RTN4_HUMAN (141-776): 1.48e-105: 352: 30.02
+	Hs
		895290 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		RTN4_HUMAN (141-776): 1.48e-105: 352: 30.02
+	Hs
		1079968 RB11B_HUMAN (4-184): 2.97e-73: 221: 32.79		RTN4_HUMAN (141-776): 1.48e-105: 352: 30.02
+	Hs
		896687 RAB14_HUMAN (4-185): 2.1e-73: 221: 29.35		RTN4_HUMAN (141-776): 1.48e-105: 352: 30.02
+	At
		189211 RAE1A_ARATH (4-184): 5.83e-74: 223: 32.07		RTNLB_ARATH (572-776): 1.07e-75: 248: 22.17
+	At
		656920 RAE1C_ARATH (4-186): 5.57e-75: 226: 31.50		RTNLD_ARATH (571-776): 9.91e-75: 245: 23.04
+	At
		189208 RAE1A_ARATH (4-184): 5.83e-74: 223: 32.07		RTNLD_ARATH (571-776): 9.91e-75: 245: 23.04
+	At
		189210 RAE1A_ARATH (4-184): 5.83e-74: 223: 32.07		RTNLA_ARATH (572-776): 1.66e-74: 245: 21.23
+	At
		1324948 RAD2B_ARATH (4-187): 7.26e-77: 230: 30.93		RTNLH_ARATH (551-772): 5.52e-66: 221: 20.09
+	At
		1341181 RABD1_ARATH (4-185): 1.24e-84: 249: 33.69		RTNLL_ARATH (566-774): 1.84e-46: 166: 13.74
+	Hs
		297806 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		K0754_HUMAN (2-293): 5.2e-12: 72.1: 13.42
+	Hs
		297829 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		K0754_HUMAN (2-293): 5.2e-12: 72.1: 13.42
+	Hs
		297805 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		K0754_HUMAN (2-293): 5.2e-12: 72.1: 13.42