HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30442766, 30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 100
+	Hs
		261627 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00
+	Hs
		350196 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		894738 RAB8A_HUMAN (4-185): 2.24e-84: 249: 36.02		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		1070209 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		261663 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00
+	Hs
		349991 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		850565 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		350050 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		350502 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		263133 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		926209 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		263244 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		261626 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00
+	Hs
		348586 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		349205 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		348604 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		348898 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		263131 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56
+	Hs
		349234 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		VAMP2_HUMAN (8-84): 1.68e-22: 85.8: 87.01
+	Hs
		263132 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		SC22B_HUMAN (8-97): 4.57e-21: 84.7: 25.56