HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 536
+	Hs
		349836 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		349095 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		SRC_HUMAN (1-536): 0: 651: 100.00
+	Rn
		589762 RASH_RAT (1-188): 8.6e-78: 232: 85.64		SRC_RAT (1-536): 0: 644: 97.95
+	Hs
		522882 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		SRC_HUMAN (1-536): 0: 651: 100.00
+	Hs
		349806 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		433358 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		348473 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		349069 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		349066 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		FYN_HUMAN (1-536): 0: 598: 68.39
+	Hs
		433312 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		433306 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		YES_HUMAN (1-536): 0: 604: 73.85
+	Hs
		349807 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		433769 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		348474 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		349070 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		LYN_HUMAN (1-531): 0: 532: 52.44
+	Hs
		349949 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		ABL2_HUMAN (11-536): 3.03e-170: 514: 39.03
+	Hs
		349172 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		ABL2_HUMAN (11-536): 3.03e-170: 514: 39.03
+	Hs
		350101 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		BTK_HUMAN (43-527): 1.18e-154: 458: 34.35
+	Hs
		348630 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		BTK_HUMAN (43-527): 1.18e-154: 458: 34.35
+	Hs
		349264 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		BTK_HUMAN (43-527): 1.18e-154: 458: 34.35