HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: DEP1B (Q8WUY9)
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)
Gene: DEPDC1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 529
+	Hs
		350395 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DEP1B_HUMAN (1-529): 0: 559: 100.00
+	Hs
		1070323 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		DEP1B_HUMAN (1-529): 0: 559: 100.00
+	Hs
		349525 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DEP1B_HUMAN (1-529): 0: 559: 100.00
+	Hs
		914247 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		DEP1B_HUMAN (1-529): 0: 559: 100.00
+	Hs
		895206 RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52		DEP1B_HUMAN (1-529): 0: 559: 100.00
+	Hs
		64637 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RHG32_HUMAN (173-497): 2.77e-61: 220: 14.54
+	Hs
		64708 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		RHG32_HUMAN (173-497): 2.77e-61: 220: 14.54
+	Hs
		350325 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RHG12_HUMAN (78-393): 5.6e-55: 200: 16.31
+	Hs
		49624 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		RHG10_HUMAN (66-528): 1.13e-56: 204: 13.10
+	Hs
		350207 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		RHG31_HUMAN (243-402): 4.62e-35: 142: 20.71
+	Hs
		914206 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		RHG18_HUMAN (195-416): 1.91e-38: 151: 15.88