Protein: EPCAM
Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)

Gene: EPCAM
Organism: Homo sapiens
Interactions: 42
UniProt ID: P16422

Gene Ontology (top 5):
GO:0001657 - ureteric bud development
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0008284 - positive regulation of cell population proliferation
GO:0009986 - cell surface

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

596571

NTRK3
NT-3 growth factor receptor

1

4

High-throughput

0.646

High

563136

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.602

High

596560

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

596559

EPCAM
Epithelial cell adhesion molecule

1

0

Small-scale

0.546

High

337858

CLD7
Claudin-7

1

2

High-throughput

0.536

High

484042

PGFRB
Platelet-derived growth factor receptor beta

1

3

High-throughput

0.500

High

541317

FGFR1
Fibroblast growth factor receptor 1

1

3

High-throughput

0.500

High

596561

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.500

High

596581

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.493

High

596583

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.493

High

555856

CADH1
Cadherin-1

1

0

High-throughput

0.493

High

596562

CALR
Calreticulin

1

0

High-throughput

0.493

High

596570

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

High-throughput

0.493

High

362714

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

410591

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

2

High-throughput

0.479

High

463896

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

5

High-throughput

0.479

High

596572

DDR2
Discoidin domain-containing receptor 2

1

3

High-throughput

0.479

High

299055

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

342737

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

402514

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.458

High

576154

PO2F1
POU domain, class 2, transcription factor 1

1

0

Small-scale

0.458

High

596563

BASI
Basigin

1

0

High-throughput

0.458

High

596565

BAP31
B-cell receptor-associated protein 31

1

0

Small-scale

0.458

High

596566

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

596569

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

596577

RHOU
Rho-related GTP-binding protein RhoU

1

0

High-throughput

0.458

High

596568

S39AE
Metal cation symporter ZIP14

1

3

High-throughput

0.445

High

596573

S39AC
Zinc transporter ZIP12

1

3

High-throughput

0.445

High

596576

S39A5
Zinc transporter ZIP5

1

3

High-throughput

0.445

High

596579

S39AB
Zinc transporter ZIP11

1

3

High-throughput

0.445

High

388364

B3AT
Band 3 anion transport protein

1

0

High-throughput

0.426

High

596575

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

479304

P3
P3 protein

1

1

High-throughput

0.407

High

596574

NTCP5
Sodium/bile acid cotransporter 5

1

1

High-throughput

0.407

High

596567

DUS4
Dual specificity protein phosphatase 4

2

0

High-throughput

0.298

High

596564

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.268

Low

596580

NEK7
Serine/threonine-protein kinase Nek7

1

0

High-throughput

0.268

Low

273253

T22D2
TSC22 domain family protein 2

1

0

Small-scale

0.251

Low

596584

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

596578

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.232

Low

596582

MF14A
Hippocampus abundant transcript 1 protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025