Protein: CLD7
Claudin-7 (CLDN-7)

Gene: CLD7, CLDN7
Organism: Homo sapiens
Interactions: 85
UniProt ID: O95471

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005886 - plasma membrane
GO:0005923 - bicellular tight junction
GO:0007155 - cell adhesion
GO:0016323 - basolateral plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

337868

EMP3
Epithelial membrane protein 3

2

5

High-throughput

0.783

High

337878

NKG7
Protein NKG7

2

0

High-throughput

0.742

High

337852

CLD7
Claudin-7

1

6

High-throughput

0.621

High

220331

LAT
Linker for activation of T-cells family member 1

2

2

High-throughput

0.606

High

225439

ITM2A
Integral membrane protein 2A

2

2

High-throughput

0.606

High

258627

G37L1
G-protein coupled receptor 37-like 1

2

4

High-throughput

0.606

High

295665

UPK1B
Uroplakin-1b

2

7

High-throughput

0.606

High

328615

VAMP5
Vesicle-associated membrane protein 5

2

2

High-throughput

0.606

High

337854

TNFA
Tumor necrosis factor

2

2

High-throughput

0.606

High

337856

ASGR1
Asialoglycoprotein receptor 1

2

5

High-throughput

0.606

High

337860

CD53
Leukocyte surface antigen CD53

2

6

High-throughput

0.606

High

337862

CD72
B-cell differentiation antigen CD72

2

6

High-throughput

0.606

High

337873

MALL
MAL-like protein

2

6

High-throughput

0.606

High

337877

VAMP3
Vesicle-associated membrane protein 3

2

2

High-throughput

0.606

High

337887

VSTM1
V-set and transmembrane domain-containing protein 1

2

2

High-throughput

0.606

High

337889

TSN33
Tetraspanin-33

2

5

High-throughput

0.606

High

337906

FXYD6
FXYD domain-containing ion transport regulator 6

2

1

High-throughput

0.606

High

337917

LPAR3
Lysophosphatidic acid receptor 3

2

6

High-throughput

0.606

High

337857

TACD2
Tumor-associated calcium signal transducer 2

2

2

Small-scale

0.601

High

139165

UPK2
Uroplakin-2

2

0

High-throughput

0.580

High

335532

BMP10
Bone morphogenetic protein 10

2

0

High-throughput

0.580

High

337859

TMM11
Transmembrane protein 11, mitochondrial

2

0

High-throughput

0.580

High

337872

NIPA4
Magnesium transporter NIPA4

2

0

High-throughput

0.580

High

337876

SREC
Scavenger receptor class F member 1

2

0

High-throughput

0.580

High

337880

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.580

High

337882

TTMP
TPA-induced transmembrane protein

2

0

High-throughput

0.580

High

337883

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.580

High

337884

RTP2
Receptor-transporting protein 2

2

0

High-throughput

0.580

High

337885

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.580

High

337886

OLFM4
Olfactomedin-4

2

0

High-throughput

0.580

High

337905

TM147
BOS complex subunit TMEM147

2

0

High-throughput

0.580

High

337912

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

337914

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.580

High

179783

BET1
BET1 homolog

2

1

High-throughput

0.553

High

280080

SC22B
Vesicle-trafficking protein SEC22b

2

1

High-throughput

0.553

High

336149

CNIH1
Protein cornichon homolog 1

2

1

High-throughput

0.553

High

337861

MAL
Myelin and lymphocyte protein

2

6

High-throughput

0.553

High

337863

IBP5
Insulin-like growth factor-binding protein 5

2

5

High-throughput

0.553

High

337871

CXCL9
C-X-C motif chemokine 9

2

2

High-throughput

0.553

High

337881

TM128
Transmembrane protein 128

2

1

High-throughput

0.553

High

337888

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

2

High-throughput

0.553

High

337890

ANR46
Ankyrin repeat domain-containing protein 46

2

1

High-throughput

0.553

High

337895

CYAC3
Lysosomal membrane ascorbate-dependent ferrireductase CYB561A3

2

3

High-throughput

0.553

High

337910

RPRM
Protein reprimo

2

2

High-throughput

0.553

High

337911

TM140
Transmembrane protein 140

2

1

High-throughput

0.553

High

337919

ERG28
Ergosterol biosynthetic protein 28 homolog

2

1

High-throughput

0.553

High

337853

TSN15
Tetraspanin-15

1

6

High-throughput

0.536

High

337858

EPCAM
Epithelial cell adhesion molecule

1

2

High-throughput

0.536

High

337893

SYNE4
Nesprin-4

1

2

High-throughput

0.523

High

337896

SCRB1
Scavenger receptor class B member 1

1

1

High-throughput

0.515

High

337870

ZO1
Tight junction protein 1

1

20

Small-scale

0.501

High

337866

AQP2
Aquaporin-2

1

4

Small-scale

0.481

High

337891

TARG1
Trafficking regulator of GLUT4 1

1

5

High-throughput

0.481

High

63631

A5PKU2
TUSC5 protein

1

5

High-throughput

0.470

High

337867

GLP1R
Glucagon-like peptide 1 receptor

1

0

Small-scale

0.460

High

337908

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.460

High

58643

SRTM1
Serine-rich and transmembrane domain-containing protein 1

2

0

High-throughput

0.316

High

156545

C56D2
Transmembrane reductase CYB561D2

2

0

High-throughput

0.316

High

208940

CYB5B
Cytochrome b5 type B

2

0

High-throughput

0.316

High

329611

LERL1
Leptin receptor overlapping transcript-like 1

2

0

High-throughput

0.316

High

337855

APOD
Apolipoprotein D

2

0

High-throughput

0.316

High

337864

PPLA
Phospholamban

2

0

High-throughput

0.316

High

337865

CO4A5

2

0

High-throughput

0.316

High

337869

EP3B
Epididymal secretory protein E3-beta

2

0

High-throughput

0.316

High

337879

TMM44
Transmembrane protein 44

2

0

High-throughput

0.316

High

337892

LSME2
Leucine-rich single-pass membrane protein 2

2

0

High-throughput

0.316

High

337894

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.316

High

337897

B2CL2
Bcl-2-like protein 2

2

0

High-throughput

0.316

High

337899

SCAM4
Secretory carrier-associated membrane protein 4

2

0

High-throughput

0.316

High

337900

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

0

High-throughput

0.316

High

337901

GIMA5
GTPase IMAP family member 5

2

0

High-throughput

0.316

High

337902

FXDC2
Fatty acid hydroxylase domain-containing protein 2

2

0

High-throughput

0.316

High

337903

CYBC1
Cytochrome b-245 chaperone 1

2

0

High-throughput

0.316

High

337907

UN93B
Protein unc-93 homolog B1

2

0

High-throughput

0.316

High

337909

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

337913

S38A7
Sodium-coupled neutral amino acid transporter 7

2

0

High-throughput

0.316

High

337915

CLN6
Ceroid-lipofuscinosis neuronal protein 6

2

0

High-throughput

0.316

High

337916

NDUBB
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial

2

0

High-throughput

0.316

High

337918

PGAP2
Acyltransferase PGAP2

2

0

High-throughput

0.316

High

337920

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.316

High

337898

HGD
Homogentisate 1,2-dioxygenase

1

0

High-throughput

0.282

High

337904

RHXF2
Rhox homeobox family member 2

1

0

High-throughput

0.282

High

337875

NNTM
NAD(P) transhydrogenase, mitochondrial

1

0

High-throughput

0.269

Low

337874

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025