Protein: TACD2
Tumor-associated calcium signal transducer 2 (Cell surface glycoprotein Trop-2) (Membrane component chromosome 1 surface marker 1) (Pancreatic carcinoma marker protein GA733-1)

Gene: TACD2, TACSTD2
Organism: Homo sapiens
Interactions: 133
UniProt ID: P09758

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0007601 - visual perception
GO:0009925 - basal plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

486553

KR108
Keratin-associated protein 10-8

2

1

High-throughput

0.606

High

486585

KRA13
Keratin-associated protein 1-3

2

1

High-throughput

0.606

High

337857

CLD7
Claudin-7

2

2

Small-scale

0.601

High

486580

KRA52
Keratin-associated protein 5-2

2

0

High-throughput

0.580

High

395360

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

67122

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

1

High-throughput

0.536

High

164516

TNPO2
Transportin-2

1

2

High-throughput

0.536

High

251189

RNBP6
Ran-binding protein 6

1

2

High-throughput

0.536

High

273156

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

3

High-throughput

0.536

High

318107

IPO13
Importin-13

1

4

High-throughput

0.536

High

344386

TBCD8
TBC1 domain family member 8

1

3

High-throughput

0.536

High

486542

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

1

High-throughput

0.536

High

486548

EI2BB
Translation initiation factor eIF2B subunit beta

1

2

High-throughput

0.536

High

486556

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

1

High-throughput

0.536

High

486559

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

High-throughput

0.536

High

486572

TBC9B
TBC1 domain family member 9B

1

3

High-throughput

0.536

High

486582

MON2
Protein MON2 homolog

1

1

High-throughput

0.536

High

486593

CIP2A
Protein CIP2A

1

1

High-throughput

0.536

High

486599

TNPO1
Transportin-1

1

2

High-throughput

0.536

High

486602

SGSM3
Small G protein signaling modulator 3

1

3

High-throughput

0.536

High

486613

XPO4
Exportin-4

1

1

High-throughput

0.536

High

486617

TBB1
Tubulin beta-1 chain

1

1

High-throughput

0.536

High

486623

EI2BG
Translation initiation factor eIF2B subunit gamma

1

1

High-throughput

0.536

High

486635

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

High-throughput

0.536

High

486636

IPO11
Importin-11

1

2

High-throughput

0.536

High

486642

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

1

High-throughput

0.536

High

486644

RBGP1
Rab GTPase-activating protein 1

1

5

High-throughput

0.536

High

486646

TNPO3
Transportin-3

1

3

High-throughput

0.536

High

64751

RIMC1
RAB7A-interacting MON1-CCZ1 complex subunit 1

1

0

High-throughput

0.513

High

137175

EXOC5
Exocyst complex component 5

1

0

High-throughput

0.513

High

167054

GEMI2
Gem-associated protein 2

1

0

High-throughput

0.513

High

208012

TTI1
TELO2-interacting protein 1 homolog

1

0

High-throughput

0.513

High

248830

GSDME
Gasdermin-E

1

0

High-throughput

0.513

High

261691

HUS1
Checkpoint protein HUS1

1

0

High-throughput

0.513

High

271658

HIP1R
Huntingtin-interacting protein 1-related protein

1

0

High-throughput

0.513

High

282347

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.513

High

299917

CBPD
Carboxypeptidase D

1

0

High-throughput

0.513

High

316594

ST17B
Serine/threonine-protein kinase 17B

1

0

High-throughput

0.513

High

486538

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

486540

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

0

High-throughput

0.513

High

486541

NF1
Neurofibromin

1

0

High-throughput

0.513

High

486545

TNFL9
Tumor necrosis factor ligand superfamily member 9

1

0

High-throughput

0.513

High

486546

MTOR
Serine/threonine-protein kinase mTOR

1

0

High-throughput

0.513

High

486550

NUP98
Nuclear pore complex protein Nup98-Nup96

1

0

High-throughput

0.513

High

486552

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.513

High

486554

PRAME
Melanoma antigen preferentially expressed in tumors

1

0

High-throughput

0.513

High

486555

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.513

High

486557

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.513

High

486558

ITPK1
Inositol-tetrakisphosphate 1-kinase

1

0

High-throughput

0.513

High

486560

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.513

High

486564

S45A4
Solute carrier family 45 member 4

1

0

High-throughput

0.513

High

486565

DOP1A
Protein DOP1A

1

0

High-throughput

0.513

High

486566

SYVM
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

486568

DEP1A
DEP domain-containing protein 1A

1

0

High-throughput

0.513

High

486571

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.513

High

486573

INT3
Integrator complex subunit 3

1

0

High-throughput

0.513

High

486575

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.513

High

486576

TTI2
TELO2-interacting protein 2

1

0

High-throughput

0.513

High

486577

INT5
Integrator complex subunit 5

1

0

High-throughput

0.513

High

486578

SARM1
NAD(+) hydrolase SARM1

1

0

High-throughput

0.513

High

486581

SETX
Probable helicase senataxin

1

0

High-throughput

0.513

High

486586

WDFY3
WD repeat and FYVE domain-containing protein 3

1

0

High-throughput

0.513

High

486587

RPTOR
Regulatory-associated protein of mTOR

1

0

High-throughput

0.513

High

486588

GPD1L
Glycerol-3-phosphate dehydrogenase 1-like protein

1

0

High-throughput

0.513

High

486591

EXOC6
Exocyst complex component 6

1

0

High-throughput

0.513

High

486596

ELYS
Protein ELYS

1

0

High-throughput

0.513

High

486600

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

0

High-throughput

0.513

High

486601

SAAL1
Protein SAAL1

1

0

High-throughput

0.513

High

486603

INT4
Integrator complex subunit 4

1

0

High-throughput

0.513

High

486604

SYNM
Asparaginyl-tRNA synthetase

1

0

High-throughput

0.513

High

486605

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.513

High

486606

XPO6
Exportin-6

1

0

High-throughput

0.513

High

486608

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.513

High

486610

NUP85
Nuclear pore complex protein Nup85

1

0

High-throughput

0.513

High

486612

HYCCI
Hyccin

1

0

High-throughput

0.513

High

486615

BTBD1
BTB/POZ domain-containing protein 1

1

0

High-throughput

0.513

High

486616

INT2
Integrator complex subunit 2

1

0

High-throughput

0.513

High

486618

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.513

High

486621

CELR2
Cadherin EGF LAG seven-pass G-type receptor 2

1

0

High-throughput

0.513

High

486624

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

486625

SOSSC
SOSS complex subunit C

1

0

High-throughput

0.513

High

486627

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

0

High-throughput

0.513

High

486629

MDN1
Midasin

1

0

High-throughput

0.513

High

486630

INT7
Integrator complex subunit 7

1

0

High-throughput

0.513

High

486631

SACS
Sacsin

1

0

High-throughput

0.513

High

486632

MTCH1
Mitochondrial carrier homolog 1

1

0

High-throughput

0.513

High

486633

CNOT8
CCR4-NOT transcription complex subunit 8

1

0

High-throughput

0.513

High

486634

DDX20
Probable ATP-dependent RNA helicase DDX20

1

0

High-throughput

0.513

High

486637

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.513

High

486638

TIM
Protein timeless homolog

1

0

High-throughput

0.513

High

486640

COG5
Conserved oligomeric Golgi complex subunit 5

1

0

High-throughput

0.513

High

486641

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.513

High

486643

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.513

High

486645

DCAF1
DDB1- and CUL4-associated factor 1

1

0

High-throughput

0.513

High

486607

ROAA
Heterogeneous nuclear ribonucleoprotein A/B

1

0

High-throughput

0.493

High

85234

RBG10
Rab GTPase-activating protein 1-like, isoform 10

1

1

High-throughput

0.489

High

486592

TBC15
TBC1 domain family member 15

1

5

High-throughput

0.489

High

486595

TB22A
TBC1 domain family member 22A

1

5

High-throughput

0.489

High

486628

TB22B
TBC1 domain family member 22B

1

5

High-throughput

0.489

High

486598

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

374354

RASH
GTPase HRas

1

0

High-throughput

0.458

High

486539

VATB1
V-type proton ATPase subunit B, kidney isoform

1

0

High-throughput

0.458

High

486543

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

486547

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

486622

ANLN
Anillin

1

0

High-throughput

0.458

High

348825

CLD1
Claudin-1

1

2

Small-scale

0.445

High

486544

VATA
V-type proton ATPase catalytic subunit A

1

1

High-throughput

0.445

High

486549

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.426

High

486609

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.426

High

486639

CP8B1
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase

2

0

High-throughput

0.328

High

244304

NPA1P
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.279

Low

328774

UNC5C
Netrin receptor UNC5C

1

0

High-throughput

0.279

Low

486551

DPOE2
DNA polymerase epsilon subunit 2

1

0

High-throughput

0.279

Low

486561

UBE3C
Ubiquitin-protein ligase E3C

1

0

High-throughput

0.279

Low

486562

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

0

High-throughput

0.279

Low

486563

SDK2
Protein sidekick-2

1

0

High-throughput

0.279

Low

486569

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

0

High-throughput

0.279

Low

486574

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

486579

THADA
tRNA

1

0

High-throughput

0.279

Low

486583

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

486584

RTTN
Rotatin

1

0

High-throughput

0.279

Low

486589

CCYL1
Cyclin-Y-like protein 1

1

0

High-throughput

0.279

Low

486590

DGLB
Diacylglycerol lipase-beta

1

0

High-throughput

0.279

Low

486594

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

486597

AP3S1
AP-3 complex subunit sigma-1

1

0

High-throughput

0.279

Low

486611

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.279

Low

486614

NRSN2
Neurensin-2

1

0

High-throughput

0.279

Low

486619

NSUN3
tRNA

1

0

High-throughput

0.279

Low

486620

K1586
E3 SUMO-protein ligase KIAA1586

1

0

High-throughput

0.279

Low

486626

F1142
Protein FAM114A2

1

0

High-throughput

0.279

Low

486567

LCE2C
Late cornified envelope protein 2C

1

0

High-throughput

0.268

Low

486570

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

261063

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025