HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	22696230, 11709720
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 135
+	Hs
		349858 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		572365 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		349181 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58
+	Ce
		136859 RB11A_CAEEL (4-184): 7.35e-74: 223: 32.79		Q9N384_CAEEL (7-133): 8.69e-30: 106: 21.54
+	Ce
		107671 RB11A_CAEEL (4-184): 7.35e-74: 223: 32.79		G5EFI4_CAEEL (11-134): 2.56e-25: 99.2: 21.71
+	Hs
		119316 RAP1A_HUMAN (1-165): 3.2e-62: 192: 56.89		LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50
+	Hs
		119117 RALA_HUMAN (4-168): 3.3e-59: 185: 54.22		LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50
+	Hs
		880582 RRAS2_HUMAN (3-188): 6.39e-57: 179: 55.26		LEG4_HUMAN (5-134): 3.8e-36: 127: 26.28
+	Hs
		119301 RRAS2_HUMAN (3-188): 6.39e-57: 179: 55.26		LEG9_HUMAN (10-133): 2.96e-35: 126: 31.50