HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: PTK7 (Q13308)
Inactive tyrosine-protein kinase 7 (Colon carcinoma kinase 4) (CCK-4) (Protein-tyrosine kinase 7) (Pseudo tyrosine kinase receptor 7) (Tyrosine-protein kinase-like 7)
Gene: PTK7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 1070
+	Hs
		348643 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		PTK7_HUMAN (2-329): 4.66e-52: 201: 19.94
+	Hs
		350138 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		PTK7_HUMAN (2-329): 4.66e-52: 201: 19.94
+	Hs
		384608 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		NTRK1_HUMAN (555-1061): 3.09e-57: 214: 30.31
+	Hs
		384613 RAP1A_HUMAN (1-165): 3.2e-62: 192: 56.89		NTRK1_HUMAN (555-1061): 3.09e-57: 214: 30.31
+	Hs
		384167 RALA_HUMAN (4-168): 3.3e-59: 185: 54.22		NTRK1_HUMAN (555-1061): 3.09e-57: 214: 30.31
+	Hs
		507936 RAB1A_HUMAN (4-186): 2.67e-75: 226: 31.28		FGFR1_HUMAN (2-231): 7.15e-34: 142: 12.41
+	Hs
		508023 RB11B_HUMAN (4-171): 1.34e-72: 219: 34.12		FGFR1_HUMAN (2-231): 7.15e-34: 142: 12.41
+	Hs
		987290 RAB1B_HUMAN (4-186): 2.6e-74: 223: 31.44		TYRO3_HUMAN (226-605): 4.36e-27: 121: 13.17
+	Hs
		507937 RAP1A_HUMAN (1-165): 3.2e-62: 192: 56.89		FGFR1_HUMAN (2-231): 7.15e-34: 142: 12.41
+	Hs
		350405 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		TITIN_HUMAN (2-145): 6.21e-13: 75.9: 16.22
+	Hs
		350572 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO2_HUMAN (590-799): 3.13e-11: 70.1: 14.16
+	Hs
		349346 RASH_HUMAN (16-189): 5.68e-73: 219: 100.00		NTRK3_HUMAN (40-228): 3.71e-16: 85.9: 19.10
+	Hs
		914253 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		TITIN_HUMAN (2-145): 6.21e-13: 75.9: 16.22
+	Rn
		589761 RASH_RAT (16-189): 5.68e-73: 219: 100.00		NTRK1_RAT (35-241): 4.44e-10: 65.9: 19.28