HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30442766, 30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 538
+	Hs
		348836 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		350416 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		914262 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		NECT2_HUMAN (1-538): 1.67e-89: 287: 100.00
+	Hs
		348943 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		350584 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT3_HUMAN (30-389): 3.83e-72: 241: 25.00
+	Hs
		350513 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		CADM1_HUMAN (40-348): 2.54e-66: 223: 20.25
+	Hs
		348671 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NECT1_HUMAN (19-370): 6.64e-58: 203: 34.72
+	Hs
		350183 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NECT1_HUMAN (19-370): 6.64e-58: 203: 34.72
+	Hs
		348489 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		NCAM1_HUMAN (33-529): 2.22e-37: 149: 13.30
+	Hs
		348643 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13
+	Hs
		349841 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		NCAM1_HUMAN (33-529): 2.22e-37: 149: 13.30
+	Hs
		350138 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		PTK7_HUMAN (4-527): 3.59e-35: 142: 14.13
+	Hs
		349043 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92
+	Hs
		348867 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		350746 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO1_HUMAN (333-538): 1.79e-18: 91.7: 8.92
+	Hs
		350455 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		KIRR1_HUMAN (33-363): 7.38e-16: 82.9: 16.72
+	Hs
		348808 RASN_HUMAN (1-188): 6.47e-88: 257: 85.64		CADM4_HUMAN (267-538): 2.9e-12: 70.5: 11.03
+	Hs
		350572 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		ROBO2_HUMAN (449-538): 4.89e-11: 67.8: 15.15
+	Hs
		350405 RASK_HUMAN (1-188): 2.04e-84: 248: 86.24		TITIN_HUMAN (171-517): 2.2e-09: 62.8: 13.49
+	Hs
		914253 RB11A_HUMAN (4-178): 4.48e-74: 223: 33.90		TITIN_HUMAN (171-517): 2.2e-09: 62.8: 13.49