Protein: DTX1
E3 ubiquitin-protein ligase DTX1 (EC 2.3.2.27) (Protein deltex-1) (Deltex1) (hDTX1) (RING-type E3 ubiquitin transferase DTX1)

Gene: DTX1
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q86Y01

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005112 - Notch binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1205011

DTX1
E3 ubiquitin-protein ligase DTX1

3

6

Small-scale

0.840

High

919774

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

Small-scale

0.800

High

135941

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

20

High-throughput

0.698

High

849361

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

20

High-throughput

0.698

High

851838

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

High-throughput

0.698

High

895839

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

High-throughput

0.698

High

896484

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

High-throughput

0.698

High

1205017

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.698

High

804282

NOTC1
Neurogenic locus notch homolog protein 1

3

7

Small-scale

0.646

High

1138887

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.625

High

476008

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

Small-scale

0.618

High

1205012

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

7

Small-scale

0.618

High

1205016

DTX4
E3 ubiquitin-protein ligase DTX4

1

6

Small-scale

0.618

High

1205013

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

1

Small-scale

0.611

High

498305

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.580

High

998862

EP300
Histone acetyltransferase p300

1

2

Small-scale

0.552

High

1030335

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.541

High

1028395

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

0

Small-scale

0.537

High

158107

TX1B3
Tax1-binding protein 3

1

2

Small-scale

0.527

High

924678

GRB2
Growth factor receptor-bound protein 2

1

8

Small-scale

0.481

High

64212

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

2

Small-scale

0.479

High

151072

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.479

High

505252

EGR2
E3 SUMO-protein ligase EGR2

1

2

Small-scale

0.479

High

802646

CRK
Adapter molecule crk

1

4

High-throughput

0.479

High

827239

ARRB1
Beta-arrestin-1

1

2

Small-scale

0.479

High

1205014

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

3

Small-scale

0.479

High

124898

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

Small-scale

0.458

High

181624

CFLAR
CASP8 and FADD-like apoptosis regulator

1

0

Small-scale

0.458

High

965250

DEF5
Defensin alpha 5

1

0

High-throughput

0.282

High

1072774

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

Small-scale

0.249

Low

1205015

T126A
Transmembrane protein 126A

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024