HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: MPRI (P11717)
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)
Gene: IGF2R

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	30442766, 30639242, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 2491
+	Hs
		349092 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		MPRI_HUMAN (1-2491): 0: 4161: 100.00
+	Hs
		348487 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		MPRI_HUMAN (1-2491): 0: 4161: 100.00
+	Hs
		514837 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		MPRI_HUMAN (1-2491): 0: 4161: 100.00
+	Hs
		514801 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		MPRI_HUMAN (1-2491): 0: 4161: 100.00
+	Hs
		514808 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		MPRI_HUMAN (1-2491): 0: 4161: 100.00
+	Hs
		363164 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63
+	Hs
		914427 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		MRC2_HUMAN (1813-1943): 3.47e-21: 104: 21.23
+	Hs
		363025 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63
+	Hs
		362997 RAP1B_HUMAN (1-165): 1.02e-62: 193: 57.49		FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63