HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: LAT1 (Q01650)
Large neutral amino acids transporter small subunit 1 (4F2 light chain) (4F2 LC) (4F2LC) (CD98 light chain) (Integral membrane protein E16) (E16) (L-type amino acid transporter 1) (hLAT1) (Solute carrier family 7 member 5) (y+ system cationic amino acid transporter)
Gene: SLC7A5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane GO:0060252 - positive regulation of glial cell proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 507
+	Hs
		349255 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		LAT1_HUMAN (1-507): 4.36e-116: 353: 100.00
+	Hs
		348622 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		LAT1_HUMAN (1-507): 4.36e-116: 353: 100.00
+	Hs
		966066 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		LAT1_HUMAN (1-507): 4.36e-116: 353: 100.00
+	Hs
		349736 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		XCT_HUMAN (14-506): 2.59e-111: 340: 45.84
+	Hs
		350407 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		YLAT2_HUMAN (7-506): 1.02e-119: 363: 47.41
+	Hs
		349011 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		XCT_HUMAN (14-506): 2.59e-111: 340: 45.84
+	Hs
		350692 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		XCT_HUMAN (14-506): 2.59e-111: 340: 45.84
+	Hs
		349223 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		S12A2_HUMAN (49-495): 4.92e-79: 270: 13.33
+	Hs
		348593 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		S12A2_HUMAN (49-495): 4.92e-79: 270: 13.33
+	Hs
		348588 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		CTR2_HUMAN (42-422): 3.51e-81: 267: 19.42
+	Hs
		349149 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		CTR1_HUMAN (42-422): 9.57e-80: 262: 19.66
+	Hs
		873920 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		S12A2_HUMAN (49-495): 4.92e-79: 270: 13.33
+	Hs
		348533 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		CTR1_HUMAN (42-422): 9.57e-80: 262: 19.66
+	Hs
		854884 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CTR2_HUMAN (42-422): 3.51e-81: 267: 19.42
+	Hs
		676544 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		CTR1_HUMAN (42-422): 9.57e-80: 262: 19.66
+	Hs
		350004 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		S12A2_HUMAN (49-495): 4.92e-79: 270: 13.33
+	Hs
		349996 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CTR2_HUMAN (42-422): 3.51e-81: 267: 19.42
+	Hs
		854867 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		CTR2_HUMAN (42-422): 3.51e-81: 267: 19.42
+	Hs
		349913 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		CTR1_HUMAN (42-422): 9.57e-80: 262: 19.66
+	Hs
		676529 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		CTR1_HUMAN (42-422): 9.57e-80: 262: 19.66