HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: GNAS2 (P63092)
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Adenylate cyclase-stimulating G alpha protein)
Gene: GNAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 1 others more... GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 189 Hs			1 394
+	Hs
		348605 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		GNAS2_HUMAN (1-394): 1.94e-179: 506: 100.00
+	Hs
		349192 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		GNAQ_HUMAN (11-394): 9.45e-151: 432: 38.02
+	Hs
		349793 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83
+	Hs
		391368 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83
+	Hs
		349815 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNAI3_HUMAN (1-394): 1.06e-155: 444: 38.58
+	Hs
		391371 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GNAI2_HUMAN (1-394): 1.99e-158: 451: 38.83
+	Hs
		450998 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GNAO_HUMAN (1-394): 2.43e-153: 438: 40.66
+	Hs
		349908 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNA11_HUMAN (11-394): 1.04e-146: 421: 38.80
+	Hs
		670449 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GNA11_HUMAN (11-394): 1.04e-146: 421: 38.80
+	Hs
		325962 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		GNA14_HUMAN (11-394): 4.75e-146: 420: 38.28
+	Hs
		349832 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		GNAT1_HUMAN (12-394): 1.69e-142: 410: 37.86