Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: GNDS (Q12967)
Ral guanine nucleotide dissociation stimulator (RalGDS) (Ral guanine nucleotide exchange factor) (RalGEF)
Gene: RALGDS

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.852

The method score is based on:

Property Details
Experiments 7809086, 10783161, 21988832
Identification Methods pull down, two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains RA~Ras, Ras~RasGEF, Ras~RasGEF_N
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007265 - Ras protein signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 189
Hs

1 914
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024