HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: UACA (Q9BZF9)
Uveal autoantigen with coiled-coil domains and ankyrin repeats
Gene: UACA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30639242, 30194290, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1416
+	Hs
		349621 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		UACA_HUMAN (3-1323): 6.02e-45: 180: 14.97
+	Hs
		348906 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		UACA_HUMAN (3-1323): 6.02e-45: 180: 14.97
+	Hs
		349000 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		1070380 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		UACA_HUMAN (3-1323): 6.02e-45: 180: 14.97
+	Hs
		1070450 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		1021405 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		350674 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		895318 RAB2A_HUMAN (4-183): 1.46e-75: 227: 32.97		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Hs
		350123 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANK3_HUMAN (75-382): 1.44e-41: 170: 18.40
+	Hs
		914450 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		KDIS_HUMAN (1-203): 7.97e-44: 177: 25.24
+	Dm
		1248518 Q962I2_DROME (4-178): 1.03e-60: 189: 51.14		Q8SWY2_DROME (43-399): 1.27e-52: 203: 14.01
+	Hs
		1070426 RAB35_HUMAN (4-187): 1.09e-82: 244: 31.28		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		350626 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		914416 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		RAI14_HUMAN (987-1410): 1.86e-29: 129: 32.55
+	Hs
		349212 RASH_HUMAN (1-188): 6.53e-87: 255: 86.77		DAPK1_HUMAN (160-397): 1.88e-10: 67.9: 11.67
+	Hs
		349001 RASN_HUMAN (1-189): 2.37e-85: 251: 85.19		ANR50_HUMAN (180-367): 2.17e-10: 67.9: 15.07
+	Mm
		71299 RAB13_MOUSE (4-188): 2.76e-75: 226: 35.05		ANR44_MOUSE (170-384): 2.66e-16: 86.8: 14.42
+	Hs
		350675 RASK_HUMAN (1-189): 8.4e-77: 229: 100.00		ANR50_HUMAN (180-367): 2.17e-10: 67.9: 15.07
+	Hs
		862018 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		DAPK1_HUMAN (160-397): 1.88e-10: 67.9: 11.67
+	Hs
		914199 RB11A_HUMAN (4-184): 2.43e-72: 219: 33.88		HACE1_HUMAN (102-374): 1.34e-09: 65.1: 25.52