Interactor 1: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Interactor 2: LAMB1 (P07942)
Laminin subunit beta-1 (Laminin B1 chain) (Laminin-1 subunit beta) (Laminin-10 subunit beta) (Laminin-12 subunit beta) (Laminin-2 subunit beta) (Laminin-6 subunit beta) (Laminin-8 subunit beta)
Gene: LAMB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.614

The method score is based on:

Property Details
Experiments 27684187, 20936779
Identification Methods affinity chromatography technology, two hybrid, two hybrid pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0030335 - positive regulation of cell migration
GO:0050679 - positive regulation of epithelial cell proliferation
GO:0062023 - collagen-containing extracellular matrix
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 390
Hs

1 1786
+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024