Interactor 1: TGFB1 (P01137)
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-1 (TGF-beta-1)]
Gene: TGFB1

Interactor 2: LRC33 (Q86YC3)
Transforming growth factor beta activator LRRC33 (Leucine-rich repeat-containing protein 33) (Negative regulator of reactive oxygen species)
Gene: NRROS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~TGF_beta, LRR_8~TGFb_propeptide
Common GO terms GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007179 - transforming growth factor beta receptor signaling pathway
GO:0009986 - cell surface
GO:0031012 - extracellular matrix
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 390
Hs

1 692
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024