HitPredict

Interactor 1: MBD3 (O95983)
Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3)
Gene: MBD3

Interactor 2: MB3L2 (Q8NHZ7)
Methyl-CpG-binding domain protein 3-like 2 (MBD3-like protein 2)
Gene: MBD3L2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.636

The method score is based on:

Property Details
Experiments 33961781, 15701600
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0006346 - DNA methylation-dependent constitutive heterochromatin formation
GO:0008327 - methyl-CpG binding
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 291
Hs

1 208
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Service provided by Combinatics, Japan

Last updated: 11Aug2025