Interactor 1: IGF2 (P01344)
Insulin-like growth factor II (IGF-II) (Somatomedin-A) (T3M-11-derived growth factor) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin]
Gene: IGF2

Interactor 2: IDE (P14735)
Insulin-degrading enzyme (EC 3.4.24.56) (Abeta-degrading protease) (Insulin protease) (Insulinase) (Insulysin)
Gene: IDE

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 1733942
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Insulin~Peptidase_M16, Insulin~Peptidase_M16_C, Insulin~Peptidase_M16_M
Common GO terms GO:0005615 - extracellular space
GO:0008286 - insulin receptor signaling pathway
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 180
Hs

1 1019
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024