HitPredict

Interactor 1: TNFA (P01375)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: TNF

Interactor 2: GUF1 (Q8N442)
Translation factor GUF1, mitochondrial (EC 3.6.5.-) (Elongation factor 4 homolog) (EF-4) (GTPase GUF1) (Ribosomal back-translocase)
Gene: GUF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 233 Hs			1 669
+	Hs
		207253 TNF14_HUMAN (75-233): 5.54e-57: 183: 27.44		GUF1_HUMAN (1-669): 0: 707: 100.00
+	Hs
		352532 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		EFTU_HUMAN (8-407): 1.99e-91: 293: 21.72
+	Hs
		352465 TNFA_HUMAN (1-233): 1.87e-111: 320: 100.00		EF2_HUMAN (67-197): 1.81e-21: 101: 40.28