Protein: LSM7
U6 snRNA-associated Sm-like protein LSm7

Gene: LSM7
Organism: Homo sapiens
Interactions: 95
UniProt ID: Q9UK45

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005688 - U6 snRNP

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1460920

LSM5
U6 snRNA-associated Sm-like protein LSm5

9

20

High-throughput

0.976

High

1460921

LSM4
U6 snRNA-associated Sm-like protein LSm4

9

20

Small-scale

0.972

High

1460917

LSM2
U6 snRNA-associated Sm-like protein LSm2

7

20

Small-scale

0.965

High

974346

LSM6
U6 snRNA-associated Sm-like protein LSm6

5

20

High-throughput

0.928

High

974292

LSM3
U6 snRNA-associated Sm-like protein LSm3

5

20

High-throughput

0.928

High

974076

RUXF
Small nuclear ribonucleoprotein F

5

20

High-throughput

0.925

High

1137191

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

3

20

Small-scale

0.866

High

974864

SMD3
Small nuclear ribonucleoprotein Sm D3

3

20

High-throughput

0.838

High

574505

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

19

High-throughput

0.811

High

974690

SMD2
Small nuclear ribonucleoprotein Sm D2

2

20

High-throughput

0.811

High

344577

LSM8
U6 snRNA-associated Sm-like protein LSm8

2

19

High-throughput

0.806

High

178057

LSM1
U6 snRNA-associated Sm-like protein LSm1

2

19

High-throughput

0.789

High

167136

GEMI2
Gem-associated protein 2

1

9

High-throughput

0.691

High

215205

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

1

11

High-throughput

0.691

High

286507

WBP4
WW domain-binding protein 4

1

6

High-throughput

0.691

High

480343

RU1C
U1 small nuclear ribonucleoprotein C

1

6

High-throughput

0.691

High

973844

RUXE
Small nuclear ribonucleoprotein E

1

16

High-throughput

0.691

High

974491

SMD1
Small nuclear ribonucleoprotein Sm D1

1

20

High-throughput

0.691

High

1138736

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

15

High-throughput

0.691

High

1241840

PRP8
Pre-mRNA-processing-splicing factor 8

1

9

High-throughput

0.691

High

1287149

PATL1
Protein PAT1 homolog 1

1

14

High-throughput

0.691

High

281114

TACC1
Transforming acidic coiled-coil-containing protein 1

2

5

Small-scale

0.654

High

1386908

DDT4L
DNA damage-inducible transcript 4-like protein

4

3

High-throughput

0.637

High

209352

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

2

18

High-throughput

0.628

High

1271899

MEPCE
7SK snRNA methylphosphate capping enzyme

2

9

High-throughput

0.611

High

352651

TCL1B
T-cell leukemia/lymphoma protein 1B

2

4

High-throughput

0.553

High

212347

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

6

High-throughput

0.536

High

216293

PPIH
Peptidyl-prolyl cis-trans isomerase H

1

6

High-throughput

0.536

High

321690

PRP6
Pre-mRNA-processing factor 6

1

20

High-throughput

0.536

High

478248

SNRPA
U1 small nuclear ribonucleoprotein A

1

16

High-throughput

0.536

High

483253

CLCA
Clathrin light chain A

1

4

High-throughput

0.536

High

483415

CLCB
Clathrin light chain B

1

4

High-throughput

0.536

High

651015

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

8

High-throughput

0.536

High

938419

NH2L1
NHP2-like protein 1

1

6

High-throughput

0.536

High

1038723

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

1

High-throughput

0.536

High

1065481

SSRP1
FACT complex subunit SSRP1

1

3

High-throughput

0.536

High

1094653

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

6

High-throughput

0.536

High

1109233

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

3

High-throughput

0.536

High

1149218

SF3A1
Splicing factor 3A subunit 1

1

7

High-throughput

0.536

High

1180385

HKDC1
Hexokinase HKDC1

1

1

High-throughput

0.536

High

1199479

UBP39
Ubiquitin carboxyl-terminal hydrolase 39

1

5

High-throughput

0.536

High

1332973

ZN511
Zinc finger protein 511

1

2

High-throughput

0.536

High

1358218

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

4

High-throughput

0.536

High

1359951

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

9

High-throughput

0.536

High

1360312

GEMI6
Gem-associated protein 6

1

5

High-throughput

0.536

High

1413408

RBM42
RNA-binding protein 42

1

12

High-throughput

0.536

High

1414616

DDX23
Probable ATP-dependent RNA helicase DDX23

1

12

High-throughput

0.536

High

1429471

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

2

High-throughput

0.536

High

1434916

STPAP
Speckle targeted PIP5K1A-regulated poly(A) polymerase

1

6

High-throughput

0.536

High

1451589

GEMI8
Gem-associated protein 8

1

5

High-throughput

0.536

High

1460919

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

7

High-throughput

0.536

High

467975

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

0

High-throughput

0.518

High

1161836

ZSC26
Zinc finger and SCAN domain-containing protein 26

1

0

High-throughput

0.518

High

1287937

LDB1
LIM domain-binding protein 1

1

0

High-throughput

0.518

High

1359839

RASF5
Ras association domain-containing protein 5

1

0

High-throughput

0.518

High

321128

PLPHP
Pyridoxal phosphate homeostasis protein

1

0

High-throughput

0.513

High

911891

GDS1
Rap1 GTPase-GDP dissociation stimulator 1

1

0

High-throughput

0.513

High

1143023

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

1292454

MTMRD
Myotubularin-related protein 13

1

0

High-throughput

0.513

High

1384047

EXOS8
Exosome complex component RRP43

1

6

High-throughput

0.508

High

1160613

SMN
Survival motor neuron protein

1

9

Small-scale

0.501

High

1387316

TMCO6
Transmembrane and coiled-coil domain-containing protein 6

1

1

High-throughput

0.489

High

170546

RAB7L
Ras-related protein Rab-7L1

1

0

High-throughput

0.486

High

1209131

EXOS6
Exosome complex component MTR3

1

13

High-throughput

0.481

High

157969

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

223412

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

248132

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

316135

RECQ4
ATP-dependent DNA helicase Q4

1

9

High-throughput

0.479

High

373447

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.479

High

406777

MYCN
N-myc proto-oncogene protein

1

9

High-throughput

0.479

High

607204

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

905267

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.479

High

980514

H4
Histone H4

1

4

High-throughput

0.479

High

1114613

CUL3
Cullin-3

1

11

High-throughput

0.479

High

1141009

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

1194445

LARP7
La-related protein 7

1

11

High-throughput

0.479

High

1252412

MEX3B
RNA-binding protein MEX3B

1

1

High-throughput

0.479

High

1327477

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

13

Small-scale

0.479

High

1336324

LS14A
Protein LSM14 homolog A

1

6

Small-scale

0.479

High

1396858

SNX27
Sorting nexin-27

1

3

High-throughput

0.479

High

1453883

AKA7G
A-kinase anchor protein 7 isoform gamma

1

12

High-throughput

0.479

High

1459246

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1460918

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

Small-scale

0.479

High

586942

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

1435428

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1452918

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.458

High

3681

NBDY
Negative regulator of P-body association

1

2

Small-scale

0.445

High

1290802

ZCH18
Zinc finger CCCH domain-containing protein 18

1

8

High-throughput

0.437

High

1393812

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.437

High

887313

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

224430

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

1

12

High-throughput

0.407

High

1412947

SYT17
Synaptotagmin-17

2

0

High-throughput

0.316

High

683140

NPY1R
Neuropeptide Y receptor type 1

1

0

High-throughput

0.265

Low

1460916

MYH13
Myosin-13

1

0

High-throughput

0.265

Low

710555

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025