Protein: TCL1B
T-cell leukemia/lymphoma protein 1B (Oncogene TCL-1B) (Oncogene TCL1B) (SYN-1) (Syncytiotrophoblast-specific protein) (TCL1/MTCP1-like protein 1)

Gene: TCL1B
Organism: Homo sapiens
Interactions: 46
UniProt ID: O95988

Gene Ontology (top 5):
GO:0019901 - protein kinase binding
GO:0035556 - intracellular signal transduction
GO:0043539 - protein serine/threonine kinase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352629

MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3

3

2

High-throughput

0.667

High

352649

MARK1
Serine/threonine-protein kinase MARK1

2

0

High-throughput

0.580

High

352628

CCDC6
Coiled-coil domain-containing protein 6

2

1

High-throughput

0.558

High

177984

LSM1
U6 snRNA-associated Sm-like protein LSm1

2

2

High-throughput

0.553

High

352624

RUXG
Small nuclear ribonucleoprotein G

2

2

High-throughput

0.553

High

352651

LSM7
U6 snRNA-associated Sm-like protein LSm7

2

4

High-throughput

0.553

High

352656

LSM5
U6 snRNA-associated Sm-like protein LSm5

2

3

High-throughput

0.553

High

352622

AKT2
RAC-beta serine/threonine-protein kinase

1

7

Small-scale

0.481

High

352621

AKT1
RAC-alpha serine/threonine-protein kinase

1

7

Small-scale

0.479

High

352619

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.457

High

352636

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.437

High

239516

MED14
Mediator of RNA polymerase II transcription subunit 14

3

0

High-throughput

0.347

High

282337

MED24
Mediator of RNA polymerase II transcription subunit 24

3

0

High-throughput

0.347

High

352626

MED22
Mediator of RNA polymerase II transcription subunit 22

3

0

High-throughput

0.347

High

352627

MED1
Mediator of RNA polymerase II transcription subunit 1

3

0

High-throughput

0.347

High

352631

ACD11
Acyl-CoA dehydrogenase family member 11

3

0

High-throughput

0.347

High

352634

HPS3
BLOC-2 complex member HPS3

3

0

High-throughput

0.347

High

352635

MED8
Mediator of RNA polymerase II transcription subunit 8

3

0

High-throughput

0.347

High

352638

MED10
Mediator of RNA polymerase II transcription subunit 10

3

0

High-throughput

0.347

High

352639

MED28
Mediator of RNA polymerase II transcription subunit 28

3

0

High-throughput

0.347

High

352640

MED20
Mediator of RNA polymerase II transcription subunit 20

3

0

High-throughput

0.347

High

352642

MED4
Mediator of RNA polymerase II transcription subunit 4

3

0

High-throughput

0.347

High

352645

MED17
Mediator of RNA polymerase II transcription subunit 17

3

0

High-throughput

0.347

High

352647

MED29
Mediator of RNA polymerase II transcription subunit 29

3

0

High-throughput

0.347

High

352648

NDE1
Nuclear distribution protein nudE homolog 1

3

0

High-throughput

0.347

High

352650

MED13
Mediator of RNA polymerase II transcription subunit 13

3

0

High-throughput

0.347

High

352653

HPS5
BLOC-2 complex member HPS5

3

0

High-throughput

0.347

High

352657

SAR1B
Small COPII coat GTPase SAR1B

3

0

High-throughput

0.347

High

352658

BIG1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1

3

0

High-throughput

0.347

High

352632

HPS6
BLOC-2 complex member HPS6

2

0

High-throughput

0.318

High

352643

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.318

High

300085

GLRX3
Glutaredoxin-3

2

0

High-throughput

0.316

High

336607

BAG4
BAG family molecular chaperone regulator 4

2

0

High-throughput

0.316

High

352625

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.316

High

352630

DRC8
Dynein regulatory complex protein 8

2

0

High-throughput

0.316

High

352633

PNMA1
Paraneoplastic antigen Ma1

2

0

High-throughput

0.316

High

352637

MEIS3
Homeobox protein Meis3

2

0

High-throughput

0.316

High

352641

PKHA3
Pleckstrin homology domain-containing family A member 3

2

0

High-throughput

0.316

High

352655

ZN330
Zinc finger protein 330

2

0

High-throughput

0.316

High

352646

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.279

Low

352620

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.249

Low

352623

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.249

Low

352644

STRN4
Striatin-4

1

0

High-throughput

0.249

Low

352652

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.249

Low

352654

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.249

Low

164504

TNPO2
Transportin-2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025