HitPredict

Interactor 1: IGKC (P01837)
Immunoglobulin kappa constant (Ig kappa chain C region MOPC 21)
Gene: IGKC

Interactor 2: GCAM (P01865)
Ig gamma-2A chain C region, membrane-bound form
Gene: Igh-1a

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	12948492, 12721618
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1-set~C1-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 107 Mm			1 398
+	Hs
		353631 IGLL1_HUMAN (4-107): 3.79e-39: 131: 38.46		IGHG1_HUMAN (2-398): 1.84e-109: 328: 66.83
+	Hs
		353698 Q8N355_HUMAN (4-107): 1.54e-38: 130: 40.39		IGHG1_HUMAN (2-398): 1.84e-109: 328: 66.83
+	Hs
		353621 IGLC1_HUMAN (4-107): 7.27e-38: 124: 41.35		IGHG1_HUMAN (2-398): 1.84e-109: 328: 66.83
+	Hs
		354030 IGLC1_HUMAN (4-107): 7.27e-38: 124: 41.35		IGHA1_HUMAN (2-373): 3.17e-65: 214: 28.39
+	Hs
		354207 HLAC_HUMAN (1-105): 2.13e-36: 128: 20.00		IGHD_HUMAN (2-373): 1.16e-57: 196: 22.53
+	Hs
		382442 HLAA_HUMAN (1-105): 1.49e-37: 131: 19.05		DRB5_HUMAN (147-326): 2e-40: 146: 17.20
+	Hs
		488244 HLAC_HUMAN (1-105): 2.13e-36: 128: 20.00		DRB5_HUMAN (147-326): 2e-40: 146: 17.20
+	Hs
		354932 HLAF_HUMAN (1-105): 2.65e-37: 130: 20.00		DRB1_HUMAN (148-326): 6.28e-39: 142: 16.76
+	Hs
		354925 HLAC_HUMAN (1-105): 2.13e-36: 128: 20.00		DRB1_HUMAN (148-326): 6.28e-39: 142: 16.76
+	Hs
		354921 DPB1_HUMAN (1-102): 1.39e-36: 126: 25.49		DRB1_HUMAN (148-326): 6.28e-39: 142: 16.76
+	Mm
		353580 IGHG1_MOUSE (5-103): 1.78e-36: 127: 29.00		LAC1_MOUSE (224-326): 3.47e-30: 113: 34.62
+	Hs
		82378 IGLL1_HUMAN (4-107): 3.79e-39: 131: 38.46		IGLL5_HUMAN (5-94): 1.62e-10: 62.5: 27.66
+	Hs
		82385 HLAF_HUMAN (1-105): 2.65e-37: 130: 20.00		IGLL5_HUMAN (5-94): 1.62e-10: 62.5: 27.66
+	Hs
		48911 IGLL5_HUMAN (4-107): 7.88e-39: 130: 41.35		IGLC7_HUMAN (4-94): 1.32e-10: 59.8: 30.53
+	Hs
		82374 IGLL5_HUMAN (4-107): 7.88e-39: 130: 41.35		IGLC6_HUMAN (4-94): 3.77e-10: 58.6: 28.42
+	Hs
		82375 IGLL5_HUMAN (4-107): 7.88e-39: 130: 41.35		IGLC3_HUMAN (4-94): 9.52e-10: 57.5: 30.53