HitPredict

Interactor 1: DRA (P01903)
HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA)
Gene: HLA-DRA

Interactor 2: HG2A (P04233)
HLA class II histocompatibility antigen gamma chain (HLA-DR antigens-associated invariant chain) (Ia antigen-associated invariant chain) (Ii) (CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide (CLIP)]
Gene: CD74

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

The method score is based on:

Property	Details
Experiments	33961781, 16242130
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0009986 - cell surface and 10 others more... GO:0012507 - ER to Golgi transport vesicle membrane GO:0019886 - antigen processing and presentation of exogenous peptide antigen via MHC class II GO:0023026 - MHC class II protein complex binding GO:0030658 - transport vesicle membrane GO:0030666 - endocytic vesicle membrane GO:0030669 - clathrin-coated endocytic vesicle membrane GO:0032588 - trans-Golgi network membrane GO:0042613 - MHC class II protein complex GO:0070062 - extracellular exosome GO:0098553 - lumenal side of endoplasmic reticulum membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	254
Hs

1	296

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024