HitPredict

Interactor 1: DQA1 (P01909)
HLA class II histocompatibility antigen, DQ alpha 1 chain (DC-1 alpha chain) (DC-alpha) (HLA-DCA) (MHC class II DQA1)
Gene: HLA-DQA1

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0098553 - lumenal side of endoplasmic reticulum membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 254 Hs			1 592
+	Hs
		382315 HLAA_HUMAN (15-251): 9.15e-85: 258: 15.94		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		3573 A0A140T9I0_HUMAN (15-251): 3.98e-81: 249: 15.54		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		354304 HLAB_HUMAN (16-219): 4.6e-77: 238: 16.51		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		488131 HLAC_HUMAN (15-216): 8.79e-77: 238: 17.29		CALX_HUMAN (1-592): 0: 786: 100.00
+	Mm
		354639 HA11_MOUSE (15-250): 2.12e-82: 252: 18.80		CALX_MOUSE (1-592): 0: 732: 90.56
+	Hs
		654086 DMB_HUMAN (104-236): 1.25e-45: 155: 30.60		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161023 DMB_HUMAN (104-236): 1.25e-45: 155: 30.60		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		382314 HLAA_HUMAN (15-251): 9.15e-85: 258: 15.94		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		382499 HLAA_HUMAN (15-251): 9.15e-85: 258: 15.94		CALR3_HUMAN (64-470): 4.22e-135: 400: 26.59
+	Hs
		488344 HLAC_HUMAN (15-216): 8.79e-77: 238: 17.29		CALR3_HUMAN (64-470): 4.22e-135: 400: 26.59
+	Hs
		653554 DRB3_HUMAN (91-218): 1.75e-50: 167: 25.78		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33