HitPredict

Interactor 1: H2B (P02283)
Histone H2B
Gene: H2B, His2B;

Interactor 2: Q94533 (Q94533)
Ribosomal protein S6 kinase (EC 2.7.11.1)
Gene: S6k

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	20463884
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 123 Dm			1 490
+	Hs
		617927 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		AKT2_HUMAN (9-401): 9.85e-155: 450: 37.91
+	Hs
		420807 H2B1J_HUMAN (3-123): 1.27e-48: 153: 81.30		AKT2_HUMAN (9-401): 9.85e-155: 450: 37.91
+	Hs
		682137 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		AKT2_HUMAN (9-401): 9.85e-155: 450: 37.91
+	Hs
		682181 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		AKT2_HUMAN (9-401): 9.85e-155: 450: 37.91
+	Hs
		617926 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		AKT1_HUMAN (9-401): 8.67e-154: 448: 38.00
+	Mm
		682111 H2B2B_MOUSE (3-123): 3.44e-49: 154: 81.30		AKT1_MOUSE (9-401): 6.97e-154: 448: 38.25
+	Hs
		420806 H2B1J_HUMAN (3-123): 1.27e-48: 153: 81.30		AKT1_HUMAN (9-401): 8.67e-154: 448: 38.00
+	Hs
		681686 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		AKT1_HUMAN (9-401): 8.67e-154: 448: 38.00
+	Hs
		681878 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		AKT1_HUMAN (9-401): 8.67e-154: 448: 38.00
+	Mm
		682113 H2B1C_MOUSE (3-123): 1.51e-48: 153: 81.30		AKT1_MOUSE (9-401): 6.97e-154: 448: 38.25
+	Hs
		568756 H2B1H_HUMAN (3-123): 5.28e-49: 154: 81.30		KAPCA_HUMAN (40-379): 1.89e-146: 424: 34.71
+	Hs
		610760 H2B1H_HUMAN (3-123): 5.28e-49: 154: 81.30		KAPCB_HUMAN (38-379): 6.47e-146: 423: 36.84
+	Hs
		241440 H2B1K_HUMAN (3-123): 2.12e-48: 152: 80.49		KAPCA_HUMAN (40-379): 1.89e-146: 424: 34.71
+	Hs
		610687 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KAPCB_HUMAN (38-379): 6.47e-146: 423: 36.84
+	Hs
		617936 H2B1O_HUMAN (3-123): 3.29e-49: 154: 82.11		KS6A3_HUMAN (2-381): 7.15e-102: 323: 24.94
+	Hs
		270378 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KS6A5_HUMAN (3-335): 1.3e-101: 323: 22.79
+	Hs
		270420 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		KS6A5_HUMAN (3-335): 1.3e-101: 323: 22.79
+	Hs
		420815 H2B1J_HUMAN (3-123): 1.27e-48: 153: 81.30		KS6A3_HUMAN (2-381): 7.15e-102: 323: 24.94
+	Hs
		707559 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KS6A3_HUMAN (2-381): 7.15e-102: 323: 24.94
+	Hs
		850663 H2B2E_HUMAN (3-123): 9.53e-49: 153: 82.11		KS6A3_HUMAN (2-381): 7.15e-102: 323: 24.94