HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: KU70 (P32807)
ATP-dependent DNA helicase II subunit 1 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit Ku70) (High affinity DNA-binding factor subunit 1)
Gene: YKU70

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	16554755, 22199229
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006325 - chromatin organization
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 131 Sc			1 602
+	Sc
		355839 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		KU70_YEAST (1-602): 0: 546: 100.00
+	Hs
		523794 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		XRCC6_HUMAN (21-565): 1.04e-150: 449: 18.83
+	Hs
		523545 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		XRCC6_HUMAN (21-565): 1.04e-150: 449: 18.83
+	Hs
		523652 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		XRCC6_HUMAN (21-565): 1.04e-150: 449: 18.83
+	Hs
		523921 H2B1A_HUMAN (29-128): 2.91e-32: 112: 80.00		XRCC6_HUMAN (21-565): 1.04e-150: 449: 18.83
+	Hs
		524943 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		XRCC5_HUMAN (25-595): 1.05e-121: 378: 13.39
+	Hs
		524806 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		XRCC5_HUMAN (25-595): 1.05e-121: 378: 13.39
+	Hs
		524869 H2B1C_HUMAN (7-128): 6.8e-46: 146: 70.97		XRCC5_HUMAN (25-595): 1.05e-121: 378: 13.39
+	Sc
		356005 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		KU80_YEAST (30-543): 1.49e-92: 299: 15.73
+	Sc
		355631 H2B1_YEAST (1-131): 2.54e-44: 143: 100.00		KU80_YEAST (30-543): 1.49e-92: 299: 15.73