HitPredict

Interactor 1: H2B1 (P02293)
Histone H2B.1 (Suppressor of Ty protein 12)
Gene: HTB1

Interactor 2: RSC2 (Q06488)
Chromatin structure-remodeling complex subunit RSC2 (RSC complex subunit RSC2) (Remodel the structure of chromatin complex subunit 2)
Gene: RSC2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.80	0.751

Property	Details
Experiments	16429126, 37968396, 21179020
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 889
+	Sc
		356020 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RSC2_YEAST (1-889): 0: 733: 100.00
+	Hs
		1066994 H2B2F_HUMAN (7-128): 7.21e-47: 149: 70.97		BRD3_HUMAN (7-385): 2.06e-68: 243: 15.92
+	Hs
		998782 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		EP300_HUMAN (4-191): 1.16e-32: 139: 18.75
+	Hs
		707606 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		EP300_HUMAN (4-191): 1.16e-32: 139: 18.75
+	Hs
		631445 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		631358 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		BRD2_HUMAN (2-255): 2.31e-29: 127: 15.89
+	Hs
		846990 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		SMCA4_HUMAN (9-122): 8.4e-29: 126: 29.92
+	Hs
		244513 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		244752 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		244011 H2B1B_HUMAN (7-128): 1.18e-45: 146: 70.16		BRD4_HUMAN (2-329): 9.37e-27: 120: 12.65
+	Hs
		1087422 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		BRD7_HUMAN (2-258): 1.02e-24: 112: 12.36
+	Hs
		1087293 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		PHIP_HUMAN (19-293): 6.82e-20: 97.9: 12.77
+	Hs
		1087228 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		PB1_HUMAN (234-742): 1.78e-19: 96.7: 14.64
+	Hs
		1274453 H2B1H_HUMAN (7-128): 3.89e-46: 147: 70.97		ASH1L_HUMAN (6-150): 7.87e-19: 94.7: 21.43
+	Sc
		355860 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		BDF1_YEAST (26-219): 5.23e-19: 94.4: 12.63
+	Hs
		1087480 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		ZMYD8_HUMAN (19-121): 2.55e-15: 82.8: 20.00
+	Sc
		355953 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RSC1_YEAST (4-149): 1.8e-12: 73.6: 18.24
+	Hs
		170383 H2B2E_HUMAN (7-128): 3.68e-46: 147: 70.97		TIF1A_HUMAN (47-132): 1.21e-11: 71: 32.22
+	Sc
		355832 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		STH1_YEAST (275-377): 2.49e-11: 69.8: 24.27
+	Sc
		355980 H2B2_YEAST (1-131): 1.46e-45: 146: 96.95		RSC4_YEAST (34-128): 1.91e-10: 66.7: 27.84