Protein: IWS1
Protein IWS1 homolog (IWS1-like protein)

Gene: IWS1
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q96ST2

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006338 - chromatin remodeling
GO:0006397 - mRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

130587

SPT5H
Transcription elongation factor SPT5

2

6

High-throughput

0.628

High

1270327

SPT6H
Transcription elongation factor SPT6

2

5

Small-scale

0.624

High

1017143

H33
Histone H3.3

2

11

High-throughput

0.611

High

1278794

HDGR2
Hepatoma-derived growth factor-related protein 2

2

4

High-throughput

0.601

High

981031

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.584

High

998713

H31
Histone H3.1

2

11

High-throughput

0.584

High

1402988

SETD2
Histone-lysine N-methyltransferase SETD2

2

6

Small-scale

0.584

High

396767

ESR1
Estrogen receptor

2

17

High-throughput

0.571

High

728397

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.561

High

1402998

AKT3
RAC-gamma serine/threonine-protein kinase

1

2

Small-scale

0.561

High

997960

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.550

High

913160

STAT2
Signal transducer and activator of transcription 2

1

1

High-throughput

0.541

High

272734

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

10

High-throughput

0.536

High

478173

SNRPA
U1 small nuclear ribonucleoprotein A

1

3

High-throughput

0.536

High

480280

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

481368

HMGB1
High mobility group protein B1

1

9

High-throughput

0.536

High

542171

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

542622

TOP2A
DNA topoisomerase 2-alpha

1

3

High-throughput

0.536

High

601821

HMGA1
High mobility group protein HMG-I/HMG-Y

1

4

High-throughput

0.536

High

872005

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

1

High-throughput

0.536

High

1065380

SSRP1
FACT complex subunit SSRP1

1

10

High-throughput

0.536

High

1117643

NOG2
Nucleolar GTP-binding protein 2

1

2

High-throughput

0.536

High

1160259

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

5

High-throughput

0.536

High

1163156

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.536

High

1191468

GRDN
Girdin

1

15

High-throughput

0.536

High

1243849

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.536

High

1247624

SAMD1
Sterile alpha motif domain-containing protein 1

1

7

High-throughput

0.536

High

1347146

WDR48
WD repeat-containing protein 48

1

9

High-throughput

0.536

High

1403001

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.536

High

777002

PPM1A
Protein phosphatase 1A

1

0

High-throughput

0.513

High

974023

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

1016369

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.513

High

1367738

PRCC
Proline-rich protein PRCC

1

0

High-throughput

0.513

High

1402987

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.513

High

1403000

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

667421

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.501

High

1042911

ERCC6
DNA excision repair protein ERCC-6

1

9

High-throughput

0.501

High

1402989

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.493

High

694386

CO8A1
Collagen alpha-1(VIII) chain

1

2

High-throughput

0.489

High

958493

ACTZ
Alpha-centractin

1

4

High-throughput

0.489

High

1219088

DAB2P
Disabled homolog 2-interacting protein

1

3

High-throughput

0.489

High

1241028

L2GL2
LLGL scribble cell polarity complex component 2

1

2

High-throughput

0.489

High

1280214

MILR1
Allergin-1

1

3

High-throughput

0.489

High

1308368

CCD71
Coiled-coil domain-containing protein 71

1

1

High-throughput

0.489

High

173257

XPO1
Exportin-1

1

4

High-throughput

0.479

High

191062

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

5

High-throughput

0.479

High

256963

H2B1K
Histone H2B type 1-K

1

20

High-throughput

0.479

High

260340

BRD4
Bromodomain-containing protein 4

1

7

High-throughput

0.479

High

537755

HSP7C
Heat shock cognate 71 kDa protein

1

5

High-throughput

0.479

High

589478

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

607020

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

697230

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

High-throughput

0.479

High

768961

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

905058

MECP2
Methyl-CpG-binding protein 2

1

4

High-throughput

0.479

High

970948

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

980183

H4
Histone H4

1

9

High-throughput

0.479

High

984923

RL31
Large ribosomal subunit protein eL31

1

1

High-throughput

0.479

High

1039350

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.479

High

1045676

TF65
Transcription factor p65

1

5

High-throughput

0.479

High

1067625

EP300
Histone acetyltransferase p300

1

10

High-throughput

0.479

High

1132912

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

7

High-throughput

0.479

High

1138534

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

1155684

EZH2
Histone-lysine N-methyltransferase EZH2

1

13

High-throughput

0.479

High

1156823

E2F4
Transcription factor E2F4

1

5

High-throughput

0.479

High

1276680

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1290117

THOC4
THO complex subunit 4

1

3

Small-scale

0.479

High

1338914

NUP43
Nucleoporin Nup43

1

15

High-throughput

0.479

High

1381847

H2B1A
Histone H2B type 1-A

1

20

High-throughput

0.479

High

1402985

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.479

High

1402991

WDR76
WD repeat-containing protein 76

1

12

High-throughput

0.479

High

1402992

RAD18
E3 ubiquitin-protein ligase RAD18

1

1

High-throughput

0.479

High

1402994

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1402996

FZR1
Fizzy-related protein homolog

1

10

High-throughput

0.479

High

1402997

RUVB2
RuvB-like 2

1

2

High-throughput

0.479

High

248053

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

1402986

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1402999

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

949972

KR103
Keratin-associated protein 10-3

1

1

High-throughput

0.439

High

157755

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.437

High

716221

ERP29
Endoplasmic reticulum resident protein 29

1

3

High-throughput

0.437

High

1121976

ARHG7
Rho guanine nucleotide exchange factor 7

1

3

High-throughput

0.437

High

1136326

EMC2
ER membrane protein complex subunit 2

1

4

High-throughput

0.437

High

1255177

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1402990

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.437

High

1402993

DYH9
Dynein axonemal heavy chain 9

1

2

High-throughput

0.437

High

1402995

DDX41
Probable ATP-dependent RNA helicase DDX41

1

0

High-throughput

0.426

High

884209

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.279

Low

1187908

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.279

Low

1218118

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

1402984

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1403002

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low

50770

ERIC2
Glutamate-rich protein 2

1

0

High-throughput

0.251

Low

62581

S35F4
Solute carrier family 35 member F4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025