HitPredict

Interactor 1: H2B2 (P02294)
Histone H2B.2
Gene: HTB2

Interactor 2: VPS75 (P53853)
Vacuolar protein sorting-associated protein 75
Gene: VPS75

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19172749
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 131 Sc			1 264
+	Sc
		355575 H2B1_YEAST (1-131): 4.04e-44: 142: 96.95		VPS75_YEAST (1-264): 1.43e-77: 237: 100.00
+	Hs
		707747 H2B1B_HUMAN (7-129): 1.29e-46: 148: 69.60		TSYL1_HUMAN (16-216): 4.07e-62: 203: 17.82
+	Hs
		707676 H2B1B_HUMAN (7-129): 1.29e-46: 148: 69.60		TSYL5_HUMAN (16-231): 2.59e-58: 192: 19.09
+	Hs
		886086 H2B1D_HUMAN (7-129): 2.49e-46: 148: 69.60		SET_HUMAN (6-216): 4.04e-59: 191: 18.27
+	Hs
		1329387 U3KQK0_HUMAN (7-130): 4.1e-49: 156: 69.05		TSYL2_HUMAN (3-230): 3.25e-50: 176: 15.32
+	Hs
		1087365 H2B2E_HUMAN (7-129): 4.62e-47: 149: 70.40		NP1L4_HUMAN (5-225): 1.39e-54: 181: 13.95
+	Hs
		420873 H2B1J_HUMAN (7-129): 7.01e-47: 149: 69.60		NP1L4_HUMAN (5-225): 1.39e-54: 181: 13.95
+	Hs
		707727 H2B1B_HUMAN (7-129): 1.29e-46: 148: 69.60		NP1L4_HUMAN (5-225): 1.39e-54: 181: 13.95
+	Hs
		876805 H2B2E_HUMAN (7-129): 4.62e-47: 149: 70.40		NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78
+	Hs
		965383 H2B2E_HUMAN (7-129): 4.62e-47: 149: 70.40		TSPY1_HUMAN (2-239): 7.88e-55: 180: 15.90
+	Hs
		707565 H2B1B_HUMAN (7-129): 1.29e-46: 148: 69.60		NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78
+	Hs
		876745 H2B1C_HUMAN (7-129): 9.01e-47: 148: 70.40		NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78
+	Hs
		1231232 H2B3B_HUMAN (7-129): 1.73e-45: 145: 64.00		NP1L4_HUMAN (5-225): 1.39e-54: 181: 13.95
+	Hs
		876845 H2B3B_HUMAN (7-129): 1.73e-45: 145: 64.00		NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78
+	Hs
		1307095 H2B1N_HUMAN (7-129): 2.75e-46: 147: 69.60		TSYL2_HUMAN (3-230): 3.25e-50: 176: 15.32
+	Rn
		961590 H2B1_RAT (7-129): 1.9e-44: 143: 67.20		TSPY1_RAT (19-218): 8.3e-51: 171: 18.91
+	Dm
		355262 H2B_DROME (8-129): 2.03e-45: 145: 67.21		Q24150_DROME (20-263): 1.34e-49: 168: 14.98
+	Dm
		355275 H2B_DROME (8-129): 2.03e-45: 145: 67.21		Q9W1G7_DROME (20-263): 1.69e-49: 168: 14.98
+	Hs
		963873 H2B1A_HUMAN (29-128): 5.73e-33: 114: 80.00		SET_HUMAN (6-216): 4.04e-59: 191: 18.27
+	Hs
		876869 H2B1A_HUMAN (29-128): 5.73e-33: 114: 80.00		NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78