HitPredict

Interactor 1: H4 (P02309)
Histone H4
Gene: HHF1

Interactor 2: ORC1 (P54784)
Origin recognition complex subunit 1 (Origin recognition complex 120 kDa subunit)
Gene: ORC1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

Property	Details
Experiments	16554755, 31263106, 20595233, 22199229, 21179020
Identification Methods	affinity chromatography technology, x-ray crystallography, pull down, tandem affinity purification
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	BAH~CENP-T_C
Common GO terms	GO:0005634 - nucleus
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 103 Sc			1 914
+	Sc
		356161 H4_YEAST (1-103): 5.28e-47: 147: 100.00		SIR3_YEAST (1-914): 0: 587: 26.50
+	Hs
		917216 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		ORC1_HUMAN (155-908): 9.77e-118: 381: 21.21
+	Hs
		917812 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		CDC6_HUMAN (252-914): 9.21e-107: 343: 18.48
+	At
		287544 H4_ARATH (18-103): 5.22e-41: 132: 89.54		CDC6A_ARATH (323-913): 4.99e-91: 300: 16.88
+	Hs
		217791 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		ORC4_HUMAN (443-840): 4.19e-80: 268: 13.51
+	Sc
		356648 H4_YEAST (1-103): 5.28e-47: 147: 100.00		ORC4_YEAST (385-711): 1.69e-45: 174: 13.51
+	Hs
		874788 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		TERA_HUMAN (420-667): 3.72e-25: 114: 10.00
+	Hs
		722207 H4_HUMAN (18-103): 1.92e-41: 133: 90.70		RFC1_HUMAN (147-633): 9.78e-20: 97.4: 12.66