Interactor 1: PLK4 (O97143)
Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase SAK)
Gene: SAK

Interactor 2: Q5U0Y0 (Q5U0Y0)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: Sin3A

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 15710747
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0031647 - regulation of protein stability
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 769
Dm

1 2062
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025