HitPredict

Interactor 1: CO2A1 (P02458)
Collagen alpha-1(II) chain (Alpha-1 type II collagen) [Cleaved into: Collagen alpha-1(II) chain; Chondrocalcin]
Gene: COL2A1

Interactor 2: C1QT2 (Q9BXJ5)
Complement C1q tumor necrosis factor-related protein 2
Gene: C1QTNF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Collagen~Collagen
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1487 Hs			1 285
+	Hs
		358617 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1QT1_HUMAN (96-280): 8e-44: 152: 28.04
+	Hs
		358582 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1QC_HUMAN (51-278): 4.3e-41: 143: 34.50
+	Hs
		358610 CO2A1_HUMAN (1-1487): 0: 779: 100.00		Q4VAQ0_HUMAN (4-277): 1.23e-33: 128: 28.20
+	Hs
		358599 CO2A1_HUMAN (1-1487): 0: 779: 100.00		CO8A2_HUMAN (40-277): 6.25e-32: 126: 32.47
+	Hs
		70495 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1T9B_HUMAN (37-194): 1.57e-26: 107: 28.48
+	Hs
		358590 CO2A1_HUMAN (1-1487): 0: 779: 100.00		C1T9A_HUMAN (82-193): 2.27e-14: 74.1: 32.14
+	Hs
		358600 CO2A1_HUMAN (1-1487): 0: 779: 100.00		CO8A1_HUMAN (33-143): 1.11e-10: 63.7: 31.37
+	Hs
		358641 CO3A1_HUMAN (1-1487): 1.29e-178: 574: 59.76		C1QT1_HUMAN (96-280): 8e-44: 152: 28.04
+	Hs
		1047982 CO4A6_HUMAN (538-1295): 8.9e-71: 264: 31.78		C1QT1_HUMAN (96-280): 8e-44: 152: 28.04
+	Hs
		441079 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		C1QT1_HUMAN (96-280): 8e-44: 152: 28.04
+	Hs
		1047979 CO4A6_HUMAN (538-1295): 8.9e-71: 264: 31.78		Q4VAQ0_HUMAN (4-277): 1.23e-33: 128: 28.20
+	Hs
		358479 CO1A1_HUMAN (3-762): 1.62e-71: 266: 41.28		CO8A2_HUMAN (40-277): 6.25e-32: 126: 32.47
+	Hs
		362576 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		C1QC_HUMAN (51-278): 4.3e-41: 143: 34.50
+	Hs
		626312 CO4A6_HUMAN (538-1295): 8.9e-71: 264: 31.78		CO8A2_HUMAN (40-277): 6.25e-32: 126: 32.47
+	Hs
		441066 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		Q4VAQ0_HUMAN (4-277): 1.23e-33: 128: 28.20
+	Hs
		441057 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		CO8A2_HUMAN (40-277): 6.25e-32: 126: 32.47
+	Hs
		441078 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		COLA1_HUMAN (5-191): 2.11e-20: 93: 20.34
+	Hs
		441048 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		C1T9A_HUMAN (82-193): 2.27e-14: 74.1: 32.14
+	Hs
		441061 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		COAA1_HUMAN (40-139): 1.95e-09: 60.1: 39.52
+	Hs
		362501 CO4A2_HUMAN (476-1293): 9.27e-66: 248: 31.45		C1QB_HUMAN (13-70): 2.95e-09: 58.3: 31.03