Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 25416956, 25910212, 24623722, 25948554, 29568061, 37071682, 16248985
Identification Methods two hybrid, affinity chromatography technology, proximity labelling technology, cross-linking study, two hybrid array, split luciferase complementation, two hybrid bait and prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament, LTD~LTD
Common GO terms GO:0005198 - structural molecule activity
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005638 - lamin filament
and 34 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 664
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024