Protein: AP2M
AP-2 complex subunit mu (Adaptin medium chain APM4) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)

Gene: AP2M, APM4
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: Q99186

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0030122 - AP-2 adaptor complex
GO:0031410 - cytoplasmic vesicle
GO:0035615 - clathrin adaptor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

691621

AP2B
AP-2 complex subunit beta

5

20

Small-scale

0.926

High

792681

AP2A
AP-2 complex subunit alpha

5

20

High-throughput

0.916

High

1025000

AP2S
AP-2 complex subunit sigma

2

19

Small-scale

0.811

High

1027325

AP1M1
AP-1 complex subunit mu-1-I

1

11

Small-scale

0.618

High

546932

SSB1
Ribosome-associated molecular chaperone SSB1

2

17

High-throughput

0.584

High

455538

PMM
Phosphomannomutase

1

0

High-throughput

0.513

High

359089

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

7

High-throughput

0.500

High

359548

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

7

High-throughput

0.500

High

367831

ENO1
Enolase 1

1

1

High-throughput

0.500

High

405161

LEU3
3-isopropylmalate dehydrogenase

1

3

High-throughput

0.500

High

408599

GAL10
Bifunctional protein GAL10 [Includes: UDP-glucose 4-epimerase

1

1

High-throughput

0.500

High

572676

ALF
Fructose-bisphosphate aldolase

1

1

High-throughput

0.500

High

626948

HSP60
Heat shock protein 60, mitochondrial

1

2

High-throughput

0.500

High

645790

HSP74
Heat shock protein SSA4

1

17

High-throughput

0.500

High

722396

XPO1
Exportin-1

1

15

High-throughput

0.489

High

814070

IF2P
Eukaryotic translation initiation factor 5B

1

3

Small-scale

0.481

High

865380

GEA1
ARF guanine-nucleotide exchange factor 1

1

3

Small-scale

0.481

High

1044872

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

1059454

VAM6
Vacuolar morphogenesis protein 6

1

2

High-throughput

0.479

High

1084592

RIO1
Serine/threonine-protein kinase RIO1

1

5

High-throughput

0.479

High

533531

AK
Aspartokinase

1

0

Small-scale

0.460

High

805480

DMA1
E3 ubiquitin-protein ligase DMA1

1

0

Small-scale

0.460

High

748116

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

1084904

ATG31
Autophagy-related protein 31

1

0

High-throughput

0.458

High

1084973

SKM1
Serine/threonine-protein kinase SKM1

1

2

High-throughput

0.457

High

448836

SNF1
Carbon catabolite-derepressing protein kinase

1

2

High-throughput

0.457

High

456476

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

2

High-throughput

0.457

High

470045

GAL7
Galactose-1-phosphate uridylyltransferase

1

1

High-throughput

0.457

High

575548

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

1

High-throughput

0.457

High

590761

HSP26
Heat shock protein 26

1

3

High-throughput

0.457

High

592609

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.457

High

597320

BIP
Endoplasmic reticulum chaperone BiP

1

12

High-throughput

0.457

High

610212

PDI
Protein disulfide-isomerase

1

1

High-throughput

0.457

High

701758

URA7
CTP synthase 1

1

1

High-throughput

0.457

High

710065

BMH1
Protein BMH1

1

4

High-throughput

0.457

High

760389

BMH2
Protein BMH2

1

4

High-throughput

0.457

High

1084781

HSP42
Heat shock protein 42

1

3

High-throughput

0.457

High

395051

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.445

High

510946

HSP77
Import motor subunit, mitochondrial

1

14

High-throughput

0.445

High

528149

HSP72
Heat shock protein SSA2

1

17

High-throughput

0.445

High

820250

SSB2
Ribosome-associated molecular chaperone SSB2

1

17

High-throughput

0.445

High

533487

RAD18
Postreplication repair E3 ubiquitin-protein ligase RAD18

1

1

Small-scale

0.439

High

665868

KPC1
Protein kinase C-like 1

1

4

Small-scale

0.439

High

708671

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

795296

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

824604

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

836986

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

779900

MID2
Cell wall integrity sensor MID2

1

0

Small-scale

0.261

Low

439179

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.261

Low

921595

CAN
Carbonic anhydrase

1

0

Small-scale

0.251

Low

1085034

ATG11
Autophagy-related protein 11

1

0

Small-scale

0.251

Low

1062894

RBX1
RING-box protein HRT1

1

0

High-throughput

0.238

Low

358388

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025