HitPredict

Interactor 1: LMNA (P02545)
Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)]
Gene: LMNA

Interactor 2: SNW1 (Q13573)
SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein)
Gene: SNW1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	20467437, 32814053
Identification Methods	affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016363 - nuclear matrix GO:0016607 - nuclear speck
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 664 Hs			1 536
+	Hs
		595213 LMNB1_HUMAN (21-580): 5.16e-50: 185: 54.37		SNW1_HUMAN (1-536): 0: 752: 100.00
+	Dr
		71502 B3DKC5_DANRE (9-597): 8e-53: 194: 65.08		Q6DRP3_DANRE (1-536): 0: 715: 84.20
+	Hs
		443499 VIME_HUMAN (27-389): 3.94e-31: 129: 28.93		SNW1_HUMAN (1-536): 0: 752: 100.00
+	Hs
		535388 GFAP_HUMAN (27-427): 1.12e-28: 121: 27.43		SNW1_HUMAN (1-536): 0: 752: 100.00
+	Hs
		422173 NFL_HUMAN (28-433): 1.96e-26: 115: 27.07		SNW1_HUMAN (1-536): 0: 752: 100.00
+	Ce
		137638 IFA2_CAEEL (18-552): 3.52e-41: 160: 25.37		YGH1_CAEEL (1-533): 0: 592: 54.80