HitPredict

Interactor 1: SPTA1 (P02549)
Spectrin alpha chain, erythrocytic 1 (Erythroid alpha-spectrin)
Gene: SPTA1

Interactor 2: ENAH (Q8N8S7)
Protein enabled homolog
Gene: ENAH

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	16336193
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030054 - cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2419 Hs			1 591
+	Hs
		360670 SPTA1_HUMAN (1-2419): 8.06e-180: 613: 100.00		EVL_HUMAN (1-374): 7.41e-27: 115: 32.71
+	Hs
		360628 SPTA1_HUMAN (1-2419): 8.06e-180: 613: 100.00		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		1068614 PLEC_HUMAN (2-1504): 2.23e-43: 177: 9.63		CTTB2_HUMAN (87-571): 1.34e-43: 169: 13.08
+	Mm
		1186641 ACTN1_MOUSE (1927-2418): 7.39e-50: 195: 26.84		HOME3_MOUSE (3-272): 5.95e-32: 128: 21.02
+	Dm
		574824 ACTN_DROME (1898-2418): 3.04e-51: 200: 26.27		HRS_DROME (174-380): 6.01e-25: 111: 24.66
+	Hs
		521586 ACTN1_HUMAN (1927-2418): 6.41e-50: 195: 26.84		TITIN_HUMAN (81-495): 1.61e-25: 114: 11.06
+	Hs
		1205722 SPTN4_HUMAN (4-762): 6.94e-37: 156: 19.50		HOME1_HUMAN (1-285): 2.84e-39: 149: 15.64
+	Mm
		561157 SPTN1_MOUSE (2-1574): 3.39e-38: 160: 15.96		TNIK_MOUSE (90-575): 1.04e-33: 139: 14.08
+	Mm
		561177 SPTN1_MOUSE (2-1574): 3.39e-38: 160: 15.96		HOME1_MOUSE (1-285): 2.08e-35: 138: 16.62
+	Mm
		82755 B9EKJ1_MOUSE (2-1574): 1.12e-37: 158: 15.92		TNIK_MOUSE (90-575): 1.04e-33: 139: 14.08
+	Mm
		82779 B9EKJ1_MOUSE (2-1574): 1.12e-37: 158: 15.92		HOME1_MOUSE (1-285): 2.08e-35: 138: 16.62
+	Dm
		962676 SPTCB_DROME (7-1114): 3.65e-45: 183: 16.37		HRS_DROME (174-380): 6.01e-25: 111: 24.66
+	Hs
		521503 ACTN1_HUMAN (1927-2418): 6.41e-50: 195: 26.84		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Ce
		103422 G4S034_CAEEL (4-1043): 9.68e-31: 135: 17.42		H2L0C7_CAEEL (14-177): 4.04e-41: 153: 26.90
+	Hs
		1045423 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		ITSN1_HUMAN (124-263): 2.96e-29: 125: 37.59
+	Hs
		1045559 SPTN1_HUMAN (2-1574): 6.04e-39: 162: 16.14		EVL_HUMAN (1-374): 7.41e-27: 115: 32.71
+	Mm
		949310 Q68FG2_MOUSE (1474-2371): 2.58e-24: 114: 15.92		TNIK_MOUSE (90-575): 1.04e-33: 139: 14.08
+	Mm
		1148446 Q68FG2_MOUSE (1474-2371): 2.58e-24: 114: 15.92		HOME1_MOUSE (1-285): 2.08e-35: 138: 16.62
+	Hs
		840569 CP250_HUMAN (4-1123): 1.7e-36: 154: 10.47		VASP_HUMAN (263-590): 7.68e-20: 93.6: 29.18
+	Hs
		1059285 GOGB1_HUMAN (818-2397): 1.05e-41: 172: 9.47		ITSN2_HUMAN (102-259): 2.05e-10: 66.1: 25.63