HitPredict

Interactor 1: OPSD (P02699)
Rhodopsin
Gene: RHO

Interactor 2: ARRS (P08168)
S-arrestin (48 kDa protein) (Retinal S-antigen) (S-AG) (Rod photoreceptor arrestin) [Cleaved into: S-arrestin short form]
Gene: SAG

Species: Bos taurus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

Property	Details
Experiments	16547131, 17360618, 23604253, 8505295
Identification Methods	molecular sieving, electron paramagnetic resonance, cosedimentation in solution, classical fluorescence spectroscopy, chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	7tm_1~Arrestin_C, 7tm_1~Arrestin_N
Common GO terms	GO:0001750 - photoreceptor outer segment GO:0009416 - response to light stimulus GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 348 Bt			1 404
+	Hs
		435859 OPSD_HUMAN (1-348): 5.22e-78: 244: 93.39		ARRS_HUMAN (2-399): 0: 605: 85.68
+	Hs
		827197 MTR1L_HUMAN (27-327): 1.79e-64: 216: 20.66		ARRB1_HUMAN (7-401): 0: 629: 55.21
+	Hs
		441649 ADRB1_HUMAN (13-342): 3.14e-64: 212: 16.49		ARRB1_HUMAN (7-401): 0: 629: 55.21
+	Hs
		674834 AGTR1_HUMAN (11-348): 3.69e-65: 211: 19.60		ARRB1_HUMAN (7-401): 0: 629: 55.21
+	Hs
		781016 OPRD_HUMAN (3-348): 1.02e-64: 210: 18.31		ARRB1_HUMAN (7-401): 0: 629: 55.21
+	Hs
		435863 OPSD_HUMAN (1-348): 5.22e-78: 244: 93.39		ARRB2_HUMAN (7-391): 0: 593: 51.23
+	Rn
		626613 AGTRA_RAT (32-348): 1.73e-63: 207: 20.86		ARRB1_RAT (7-388): 0: 620: 56.00
+	Rn
		663954 Q8VBU7_RAT (5-339): 1.36e-73: 235: 18.28		ARRB2_RAT (7-391): 0: 590: 50.86
+	Mm
		669680 AGTRA_MOUSE (32-348): 2.86e-63: 207: 20.55		ARRB1_MOUSE (7-388): 0: 617: 55.75
+	Hs
		428933 ADRB2_HUMAN (7-329): 1.28e-70: 227: 18.63		ARRB2_HUMAN (7-391): 0: 593: 51.23
+	Hs
		685813 APJ_HUMAN (11-348): 4.92e-66: 214: 18.75		ARRB2_HUMAN (7-391): 0: 593: 51.23
+	Hs
		441648 ADRB1_HUMAN (13-342): 3.14e-64: 212: 16.49		ARRB2_HUMAN (7-391): 0: 593: 51.23
+	Hs
		674827 AGTR1_HUMAN (11-348): 3.69e-65: 211: 19.60		ARRB2_HUMAN (7-391): 0: 593: 51.23
+	Hs
		685822 OPRD_HUMAN (3-348): 1.02e-64: 210: 18.31		ARRB2_HUMAN (7-391): 0: 593: 51.23
+	Hs
		435866 OPSD_HUMAN (1-348): 5.22e-78: 244: 93.39		ARRC_HUMAN (11-398): 0: 555: 48.98
+	Rn
		626614 AGTRA_RAT (32-348): 1.73e-63: 207: 20.86		ARRB2_RAT (7-391): 0: 590: 50.86
+	Dm
		409742 OPS1_DROME (6-345): 7.44e-75: 237: 25.34		ARRB_DROME (11-387): 1.89e-180: 509: 39.50
+	Dm
		409740 OPS1_DROME (6-345): 7.44e-75: 237: 25.34		ARRA_DROME (9-360): 7.5e-178: 501: 42.25