Protein: H90B3
Putative heat shock protein HSP 90-beta-3 (Heat shock protein 90-beta c) (Heat shock protein 90Bc)

Gene: H90B3, HSP90AB3P
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q58FF7

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006457 - protein folding
GO:0016887 - ATP hydrolysis activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

400940

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

20

High-throughput

0.712

High

440589

FYN
Tyrosine-protein kinase Fyn

2

20

High-throughput

0.712

High

463120

YES
Tyrosine-protein kinase Yes

2

20

High-throughput

0.712

High

897850

CDK9
Cyclin-dependent kinase 9

2

20

High-throughput

0.712

High

1060786

ACK1
Activated CDC42 kinase 1

2

20

High-throughput

0.712

High

1154373

STK11
Serine/threonine-protein kinase STK11

2

17

High-throughput

0.712

High

1202026

CDK15
Cyclin-dependent kinase 15

2

20

High-throughput

0.712

High

1202034

AKT3
RAC-gamma serine/threonine-protein kinase

2

20

High-throughput

0.712

High

363380

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.575

High

440105

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.575

High

461562

HS90A
Heat shock protein HSP 90-alpha

1

18

High-throughput

0.575

High

463562

LYN
Tyrosine-protein kinase Lyn

1

20

High-throughput

0.575

High

468452

HS90B
Heat shock protein HSP 90-beta

1

18

High-throughput

0.575

High

473430

HCK
Tyrosine-protein kinase HCK

1

20

High-throughput

0.575

High

486700

FGR
Tyrosine-protein kinase Fgr

1

20

High-throughput

0.575

High

521374

ARAF
Serine/threonine-protein kinase A-Raf

1

20

High-throughput

0.575

High

541530

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.575

High

549173

CDK4
Cyclin-dependent kinase 4

1

20

High-throughput

0.575

High

578499

BRAF
Serine/threonine-protein kinase B-raf

1

20

High-throughput

0.575

High

720246

UFO
Tyrosine-protein kinase receptor UFO

1

20

High-throughput

0.575

High

728279

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

High-throughput

0.575

High

731364

STIP1
Stress-induced-phosphoprotein 1

1

20

High-throughput

0.575

High

783593

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

20

High-throughput

0.575

High

889748

CLK3
Dual specificity protein kinase CLK3

1

20

High-throughput

0.575

High

897295

CDK7
Cyclin-dependent kinase 7

1

20

High-throughput

0.575

High

902847

BLK
Tyrosine-protein kinase Blk

1

20

High-throughput

0.575

High

908207

BMX
Cytoplasmic tyrosine-protein kinase BMX

1

20

High-throughput

0.575

High

909029

NEK4
Serine/threonine-protein kinase Nek4

1

20

High-throughput

0.575

High

1025309

CDKL1
Cyclin-dependent kinase-like 1

1

20

High-throughput

0.575

High

1054116

BTK
Tyrosine-protein kinase BTK

1

20

High-throughput

0.575

High

1065085

ITK
Tyrosine-protein kinase ITK/TSK

1

20

High-throughput

0.575

High

1118409

PTK6
Protein-tyrosine kinase 6

1

20

High-throughput

0.575

High

1119675

CDK13
Cyclin-dependent kinase 13

1

20

High-throughput

0.575

High

1158354

CDC37
Hsp90 co-chaperone Cdc37

1

17

High-throughput

0.575

High

1158792

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

19

High-throughput

0.575

High

1202019

CDKL4
Cyclin-dependent kinase-like 4

1

20

High-throughput

0.575

High

1202022

MYLK4
Myosin light chain kinase family member 4

1

20

High-throughput

0.575

High

1202024

STK35
Serine/threonine-protein kinase 35

1

20

High-throughput

0.575

High

1202028

NUAK2
NUAK family SNF1-like kinase 2

1

18

High-throughput

0.575

High

1202029

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

20

High-throughput

0.575

High

1202032

CD11A
Cyclin-dependent kinase 11A

1

20

High-throughput

0.575

High

1202033

AURKC
Aurora kinase C

1

20

High-throughput

0.575

High

1202025

ESR2
Estrogen receptor beta

1

20

High-throughput

0.514

High

135634

DNM1L
Dynamin-1-like protein

1

7

High-throughput

0.445

High

193283

SOCS1
Suppressor of cytokine signaling 1

1

20

High-throughput

0.445

High

346642

TTC4
Tetratricopeptide repeat protein 4

1

20

High-throughput

0.445

High

361271

SODC
Superoxide dismutase [Cu-Zn]

1

4

High-throughput

0.445

High

584763

NDKA
Nucleoside diphosphate kinase A

1

2

High-throughput

0.445

High

626252

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

14

High-throughput

0.445

High

640909

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

8

High-throughput

0.445

High

736920

GBP2
Guanylate-binding protein 2

1

2

High-throughput

0.445

High

788050

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.445

High

1113283

CUL3
Cullin-3

1

20

High-throughput

0.445

High

1202020

A16L1
Autophagy-related protein 16-1

1

17

High-throughput

0.445

High

1202027

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.445

High

1202030

SMYD3
Histone-lysine N-methyltransferase SMYD3

1

6

High-throughput

0.445

High

1202031

AGO3
Protein argonaute-3

1

20

High-throughput

0.445

High

483111

CLCA
Clathrin light chain A

1

0

High-throughput

0.426

High

429998

JUN
Transcription factor Jun

1

12

High-throughput

0.407

High

471060

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.407

High

484561

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

7

High-throughput

0.407

High

724094

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

5

High-throughput

0.407

High

773893

SOAT1
Sterol O-acyltransferase 1

1

6

High-throughput

0.407

High

1202021

COX15
Heme A synthase COX15

1

3

High-throughput

0.407

High

1202023

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

16

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025