Interactor 1: FINC (P02751)
Fibronectin (FN) (Cold-insoluble globulin) (CIG) [Cleaved into: Anastellin; Ugl-Y1; Ugl-Y2; Ugl-Y3]
Gene: FN1

Interactor 2: MMP2 (P08253)
72 kDa type IV collagenase (EC 3.4.24.24) (72 kDa gelatinase) (Gelatinase A) (Matrix metalloproteinase-2) (MMP-2) (TBE-1) [Cleaved into: PEX]
Gene: MMP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.876

The method score is based on:

Property Details
Experiments 28514442, 33961781, 20932906
Identification Methods affinity chromatography technology, protease assay, anti tag coimmunoprecipitation
Interaction Type physical association, cleavage reaction, protein cleavage, association

The annotation score is based on:

Property Details
Interacting Pfam domains fn1~fn2, fn2~fn2
Common GO terms GO:0001525 - angiogenesis
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007507 - heart development
and 2 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 2477
Hs

1 660
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024