Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR

Interactor 2: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.708

The method score is based on:

Property Details
Experiments 34079125, 35844135, 20029029, 24797263, unassigned2173
Identification Methods proximity labelling technology, protein complementation assay, affinity chromatography technology, ubiquitin reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005768 - endosome
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 4 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1210
Hs

1 175
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Service provided by Combinatics, Japan

Last updated: 11Aug2025