Interactor 1: EGFR (P00533)
Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
Gene: EGFR
Interactor 2: TRPV1 (Q8NER1)
Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)
Gene: TRPV1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19155296 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~GF_recep_IV, Ank_2~Recep_L_domain |
| Common GO terms | GO:0004888 - transmembrane signaling receptor activity GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0007166 - cell surface receptor signaling pathway GO:0016020 - membrane |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
