HitPredict

Interactor 1: RPOD (P00579)
RNA polymerase sigma factor RpoD (Sigma-70)
Gene: RPOD

Interactor 2: MELR (P0ACH8)
Melibiose operon regulatory protein
Gene: MELR

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.795

Property	Details
Experiments	24561554, 14982625
Identification Methods	two hybrid, genetic interference, biochemical, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HTH_18~Sigma70_r4
Common GO terms	GO:0003677 - DNA binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 613 Ec			1 302
+	Ec
		365800 RPOD_ECOLI (1-613): 0: 642: 100.00		RHAR_ECOLI (23-296): 3.31e-79: 243: 19.20
+	Ec
		365799 RPOD_ECOLI (1-613): 0: 642: 100.00		RHAS_ECOLI (23-298): 6.18e-72: 225: 16.55
+	Ec
		365851 RPOD_ECOLI (1-613): 0: 642: 100.00		YPDC_ECOLI (45-294): 4.05e-59: 192: 16.80
+	Ec
		365833 RPOD_ECOLI (1-613): 0: 642: 100.00		CHBR_ECOLI (32-298): 2.16e-53: 177: 18.73
+	Ec
		365837 RPOD_ECOLI (1-613): 0: 642: 100.00		GADX_ECOLI (44-298): 1.12e-52: 175: 17.58
+	Ec
		365818 RPOD_ECOLI (1-613): 0: 642: 100.00		ARAC_ECOLI (47-298): 2.3e-51: 172: 15.59
+	Ec
		365798 RPOD_ECOLI (1-613): 0: 642: 100.00		ADA_ECOLI (117-292): 2.16e-24: 102: 17.61
+	Ss
		1001883 SIGA_SYNY3 (187-611): 5.19e-86: 276: 37.41		P73364_SYNY3 (101-292): 2.55e-41: 145: 19.49