Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: SBA1 (P28707)
Co-chaperone protein SBA1
Gene: SBA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 16625188, 10564510, 23396352, 9632755, 15466438, 27723736, 18362168, 18719252, 20237159, 24462205, 15364569, 15879519, 26804907, 28363677, 29930177, 28537252, 31399574, 32565117, 38705392, 20159553 and 4 others

more...

Identification Methods x-ray crystallography, cross-linking study, cosedimentation in solution, affinity chromatography technology, pull down, enzymatic study, two hybrid, two hybrid array
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0032212 - positive regulation of telomere maintenance via telomerase
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 709
Sc

1 216
+ Sc
+ Hs
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024