HitPredict

Interactor 1: HSP82 (P02829)
ATP-dependent molecular chaperone HSP82 (82 kDa heat shock protein) (Heat shock protein Hsp90 heat-inducible isoform)
Gene: HSP82

Interactor 2: LYS12 (P40495)
Homoisocitrate dehydrogenase, mitochondrial (HIcDH) (EC 1.1.1.87)
Gene: LYS12

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	16429126, 31399574
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 709 Sc			1 371
+	Sc
		543875 HSC82_YEAST (1-709): 0: 973: 94.64		LYS12_YEAST (1-371): 1.6e-151: 433: 100.00
+	Sc
		365911 HSP82_YEAST (1-709): 0: 984: 100.00		IDH2_YEAST (2-371): 2.68e-141: 407: 33.95
+	Sc
		365923 HSP82_YEAST (1-709): 0: 984: 100.00		IDH1_YEAST (3-371): 2.95e-138: 399: 34.41
+	Sc
		543320 HSC82_YEAST (1-709): 0: 973: 94.64		IDH2_YEAST (2-371): 2.68e-141: 407: 33.95
+	Sc
		543332 HSC82_YEAST (1-709): 0: 973: 94.64		IDH1_YEAST (3-371): 2.95e-138: 399: 34.41
+	Sc
		365512 HSP82_YEAST (1-709): 0: 984: 100.00		LEU3_YEAST (25-371): 7.77e-113: 335: 31.25
+	Sc
		378270 HSC82_YEAST (1-709): 0: 973: 94.64		LEU3_YEAST (25-371): 7.77e-113: 335: 31.25
+	Dm
		1361640 Q9VAY2_DROME (3-680): 0: 837: 46.67		IDH3A_DROME (5-371): 1.6e-159: 453: 33.33