Protein: HGF
Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain]

Gene: HGF
Organism: Homo sapiens
Interactions: 47
UniProt ID: P14210

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000902 - cell morphogenesis
GO:0001837 - epithelial to mesenchymal transition
GO:0001889 - liver development
GO:0005102 - signaling receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

471974

MET
Hepatocyte growth factor receptor

12

20

Small-scale

0.978

High

571172

HGF
Hepatocyte growth factor

4

17

Small-scale

0.888

High

287519

LRP6
Low-density lipoprotein receptor-related protein 6

1

10

High-throughput

0.691

High

571186

NOTC1
Neurogenic locus notch homolog protein 1

1

15

High-throughput

0.691

High

571199

SORL
Sortilin-related receptor

1

14

High-throughput

0.691

High

571192

HGFA
Hepatocyte growth factor activator serine protease

1

18

Small-scale

0.666

High

253711

SRPX2
Sushi repeat-containing protein SRPX2

1

6

Small-scale

0.647

High

407754

VWF
von Willebrand factor

1

6

Small-scale

0.647

High

571190

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

6

Small-scale

0.647

High

571203

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

3

4

High-throughput

0.599

High

371059

MYC
Myc proto-oncogene protein

2

7

High-throughput

0.595

High

571187

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.573

High

571196

ATL4
ADAMTS-like protein 4

1

9

High-throughput

0.573

High

388981

FINC
Fibronectin

1

10

Small-scale

0.501

High

400219

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.501

High

410573

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

19

High-throughput

0.501

High

430713

TETN
Tetranectin

1

3

Small-scale

0.501

High

571174

PGFRA
Platelet-derived growth factor receptor alpha

1

5

High-throughput

0.501

High

571176

FGFR4
Fibroblast growth factor receptor 4

1

8

High-throughput

0.501

High

571177

TENA
Tenascin

1

17

Small-scale

0.501

High

571178

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

3

High-throughput

0.501

High

571179

EPHA2
Ephrin type-A receptor 2

1

18

High-throughput

0.501

High

571188

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

5

High-throughput

0.501

High

571189

1433G
14-3-3 protein gamma

1

3

High-throughput

0.501

High

571193

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

4

High-throughput

0.501

High

571195

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.501

High

207791

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

3

High-throughput

0.489

High

571197

KBTB6
Kelch repeat and BTB domain-containing protein 6

1

4

High-throughput

0.489

High

571198

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

4

High-throughput

0.489

High

571183

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.481

High

179670

MDM4
Protein Mdm4

1

0

High-throughput

0.480

High

399536

VTNC
Vitronectin

1

0

Small-scale

0.480

High

571180

CCND2
G1/S-specific cyclin-D2

1

0

High-throughput

0.480

High

571182

MERL
Merlin

1

0

High-throughput

0.480

High

571194

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.480

High

571200

GLIS2
Zinc finger protein GLIS2

1

0

High-throughput

0.480

High

240641

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

549037

CDK4
Cyclin-dependent kinase 4

1

1

High-throughput

0.457

High

571173

DESP
Desmoplakin

1

4

Small-scale

0.457

High

571175

SDC1
Syndecan-1

1

1

Small-scale

0.457

High

571181

SDC2
Syndecan-2

1

1

Small-scale

0.457

High

571184

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

6

High-throughput

0.457

High

571185

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

6

High-throughput

0.457

High

571191

CDK6
Cyclin-dependent kinase 6

1

1

High-throughput

0.457

High

571202

LATS2
Serine/threonine-protein kinase LATS2

1

5

High-throughput

0.457

High

571201

TRI31
E3 ubiquitin-protein ligase TRIM31

1

6

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025