Interactor 1: PBPB (P02919)
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.99.28) (Peptidoglycan TGase) (Peptidoglycan glycosyltransferase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]
Gene: mrcB

Interactor 2: PBPB (P02919)
Penicillin-binding protein 1B (PBP-1b) (PBP1b) (Murein polymerase) [Includes: Penicillin-insensitive transglycosylase (EC 2.4.99.28) (Peptidoglycan TGase) (Peptidoglycan glycosyltransferase); Penicillin-sensitive transpeptidase (EC 3.4.16.4) (DD-transpeptidase)]
Gene: mrcB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 17938168, 16858726
Identification Methods pull down, blue native page
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Transgly~Transgly, Transgly~Transpeptidase, Transgly~UB2H, Transpeptidase~Transpeptidase
Common GO terms GO:0005886 - plasma membrane
GO:0006508 - proteolysis
GO:0008360 - regulation of cell shape
GO:0008658 - penicillin binding
GO:0008955 - peptidoglycan glycosyltransferase activity
and 8 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 844
Ec

1 844
+ Ec
+ Ss
+ Ss
+ Bs
+ Ec
+ Aa
+ Sp
+ Ss
+ Ss
+ Sa
+ Sa
+ Ss
+ Sa
+ Sa
+ Ec

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Last updated: 15 Jul 2024