Protein: HACL1
2-hydroxyacyl-CoA lyase 1 (EC 4.1.2.63) (2-hydroxyphytanoyl-CoA lyase) (2-HPCL) (Phytanoyl-CoA 2-hydroxylase 2)

Gene: HACL1
Organism: Homo sapiens
Interactions: 24
UniProt ID: Q9UJ83

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001561 - fatty acid alpha-oxidation
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1460561

HACL1
2-hydroxyacyl-CoA lyase 1

2

16

High-throughput

0.840

High

896329

PEX5
Peroxisomal targeting signal 1 receptor

3

0

Small-scale

0.604

High

1419766

ASPC1
Tether containing UBX domain for GLUT4

2

0

High-throughput

0.602

High

564525

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.541

High

1161252

MK06
Mitogen-activated protein kinase 6

1

6

High-throughput

0.508

High

122570

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

2

High-throughput

0.479

High

331396

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.479

High

589981

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

696806

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

769459

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.479

High

831611

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

1436540

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

1460563

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

1

4

High-throughput

0.479

High

400038

CATA
Catalase

1

0

High-throughput

0.458

High

1128861

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1447408

ANLN
Anillin

1

0

High-throughput

0.458

High

1086718

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

High-throughput

0.438

High

1256009

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

854597

S15A1
Solute carrier family 15 member 1

1

2

High-throughput

0.407

High

1388512

ZMY19
Zinc finger MYND domain-containing protein 19

5

0

High-throughput

0.376

High

1249644

PXDC2
Plexin domain-containing protein 2

2

0

High-throughput

0.328

High

1460562

ODF2L
Protein BCAP

2

0

High-throughput

0.328

High

1330711

MAGB6
Melanoma-associated antigen B6

1

0

High-throughput

0.299

High


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Last updated: 11Aug2025